CBD_IV

Cellulose Binding Domain Type IV

• SMART accession number: SM00606
• Description: -
• Interpro abstract (IPR006584):

  This entry represents a type IV cellulose binding domain. It is a sub-domain of the carbohydrate-binding module, family 6 .

  Regarding the function, it shows endohydrolysis of 1,4-beta-d-xylosidic linkages in xylans [ (PUBMED:1938968) ].

• GO function: carbohydrate binding (GO:0030246)

There are 7822 CBD_IV domains in 6191 proteins in SMART's nrdb database.

Metabolism (metabolic pathways involving proteins which contain this domain)

% proteins involved	KEGG pathway ID	Description
27.27	map00940	Phenylpropanoid biosynthesis
27.27	map00500	Starch and sucrose metabolism
27.27	map00460	Cyanoamino acid metabolism
9.09	map00562	Inositol phosphate metabolism
9.09	map00632	Benzoate degradation via CoA ligation

This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with CBD_IV domain which could be assigned to a KEGG orthologous group, and not all proteins containing CBD_IV domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.

Structure (3D structures containing this domain)

3D Structures of CBD_IV domains in PDB

PDB code	Title
1gmm	Carbohydrate binding module CBM6 from xylanase U Clostridium thermocellum
1nae	Structure of CsCBM6-3 from Clostridium stercorarium in complex with xylotriose
1o8p	Unbound structure of CsCBM6-3 from Clostridium stercorarium
1o8s	Structure of CsCBM6-3 from Clostridium stercorarium in complex with cellobiose
1od3	Structure of CBM6-3 in complex with laminaribiose
1uxx	CBM6ct from Clostridium thermocellum in complex with xylopentaose
1uxz	Carbohydrate binding module (CBM6cm-2) from Cellvibrio mixtus lichenase 5A
1uy0	Carbohydrate binding module (CBM6cm-2) from Cellvibrio mixtus lichenase 5A in complex with glc-1,3-glc-1,4-glc-1,3-glc
1uy1	Binding sub-site dissection of a family 6 carbohydrate-binding module by X-ray crystallography and isothermal titration calorimetry
1uy2	Binding sub-site dissection of a family 6 carbohydrate-binding module by X-ray crystallography and isothermal titration calorimetry
1uy3	Binding sub-site dissection of a family 6 carbohydrate-binding module by X-ray crystallography and isothermal titration calorimetry
1uy4	Binding sub-site dissection of a family 6 carbohydrate-binding module by X-ray crystallography and isothermal titration calorimetry
1uyx	Carbohydrate binding module (CBM6cm-2) from Cellvibrio mixtus lichenase 5A in complex with cellobiose
1uyy	Carbohydrate binding module (CBM6cm-2) from Cellvibrio mixtus lichenase 5A in complex with cellotriose
1uyz	Carbohydrate binding module (CBM6cm-2) from Cellvibrio mixtus lichenase 5A in complex with xylotetraose
1uz0	Carbohydrate binding module (CBM6cm-2) from Cellvibrio mixtus lichenase 5A in complex with Glc-4Glc-3Glc-4Glc
1w9s	Structure of a beta-1,3-glucan binding CBM6 from Bacillus halodurans
1w9t	Structure of a beta-1,3-glucan binding CBM6 from Bacillus halodurans in complex with xylobiose
1w9w	Structure of a beta-1,3-glucan binding CBM6 from Bacillus halodurans in complex with laminarihexaose
2cdo	structure of agarase carbohydrate binding module in complex with neoagarohexaose
2cdp	Structure of a CBM6 in complex with neoagarohexaose
2v4v	Crystal Structure of a Family 6 Carbohydrate-Binding Module from Clostridium cellulolyticum in complex with xylose
2y8k	Structure of CtGH5-CBM6, an arabinoxylan-specific xylanase.
3c7e	Crystal structure of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase from Bacillus subtilis.
3c7f	Crystal structure of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase from bacillus subtilis in complex with xylotriose.
3c7g	Crystal structure of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase from Bacillus subtilis in complex with xylotetraose.
3c7h	Crystal structure of glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase from Bacillus subtilis in complex with AXOS-4-0.5.
3c7o	Crystal structure of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase from Bacillus subtilis in complex with cellotetraose.
5fui	5FUI
5g56	5G56
5la0	5LA0
5la1	5LA1
5la2	5LA2

Links (links to other resources describing this domain)

• INTERPRO: IPR006584