CBM_10

CBM_10

Cellulose or protein binding domain
SMART ACC:SM001064
Description:This domain is found in two distinct sets of proteins with different functions. Those found in aerobic bacteria bind cellulose (or other carbohydrates); but in anaerobic fungi they are protein binding domains, referred to as dockerin domains or docking domains. They are believed to be responsible for the assembly of a multiprotein cellulase/hemicellulase complex, similar to the cellulosome found in certain anaerobic bacteria.
InterPro ACC:IPR009031
InterPro abstract:

Plant cell wall hydrolases from aerobic microorganisms generally have a modular structure consisting of a catalytic domain linked to one or more carbohydrate-binding modules (CBMs). CBMs function to attach the enzyme to the polymeric substrate, thereby increasing the catalytic activity. Most CBMs bind cellulose and are referred to as cellulose-binding domains (CBDs), while some can also bind xylan.

GO process:carbohydrate metabolic process (GO:0005975)
GO function:cellulose binding (GO:0030248)
Family alignment:View the Family alignment or the Alignment consensus sequence
There are 456 CBM_10 domains in 265 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing CBM_10 domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing CBM_10 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:Metabolic

Relevant references for this domain

Primary literature for the CBM_10 domain is listed below. Automatically-derived, secondary literature is also available.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a CBM_10 domain which could be assigned to a KEGG orthologous group, and not all proteins containing CBM_10 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

InterProIPR009031
PfamCBM_10