CRISPR_assoc
SMART ACC:	SM001101
Description:	This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.
InterPro ACC:	IPR010179
InterPro abstract:	The CRISPR-Cas system is a prokaryotic defence mechanism against foreign genetic elements. The key elements of this defence system are the Cas proteins and the CRISPR RNA. This entry represents the Cse3 (CRISPR/Cas Subtype Ecoli protein 3, also known as CasE) family of Cas proteins. The Thermus thermophilus HB8 family member has been crystallised and found to have a structure consisting … expand The CRISPR-Cas system is a prokaryotic defence mechanism against foreign genetic elements. The key elements of this defence system are the Cas proteins and the CRISPR RNA. This entry represents the Cse3 (CRISPR/Cas Subtype Ecoli protein 3, also known as CasE) family of Cas proteins. The Thermus thermophilus HB8 family member has been crystallised and found to have a structure consisting of two domains with opposing parallel β-sheets, known as a β-sheet platform [ PUBMED:16672237 ]. This structure is similar to those found in the sex-lethal protein and poly(A)-binding protein and is consistent with an RNA-binding function. collapse
Family alignment:	View the Family alignment or the Alignment consensus sequence
There are 2 285 CRISPR_assoc domains in 2 285 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing CRISPR_assoc domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing CRISPR_assoc domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

3D structures in PDB containing this domain

Links to other resources describing this domain

InterPro	IPR010179
Pfam	CRISPR_assoc