ChtBD1

Chitin binding domain

• SMART accession number: SM00270
• Description: -
• Interpro abstract (IPR001002):

  A number of plant and fungal proteins that bind N-acetylglucosamine (e.g. solanaceous lectins of tomato and potato, plant endochitinases, the wound-induced proteins: hevein, win1 and win2, and the Kluyveromyces lactis killer toxin alpha subunit) contain this domain [ (PUBMED:1757999) ]. The domain may occur in one or more copies and is thought to be involved in recognition or binding of chitin subunits [ (PUBMED:2070799) (PUBMED:1375935) ]. In chitinases, as well as in the potato wound-induced proteins, the 43-residue domain directly follows the signal sequence and is therefore at the N terminus of the mature protein; in the killer toxin alpha subunit it is located in the central section of the protein.

• GO function: chitin binding (GO:0008061)

There are 7172 ChtBD1 domains in 3459 proteins in SMART's nrdb database.

Metabolism (metabolic pathways involving proteins which contain this domain)

% proteins involved	KEGG pathway ID	Description
100.00	map00530	Aminosugars metabolism

This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with ChtBD1 domain which could be assigned to a KEGG orthologous group, and not all proteins containing ChtBD1 domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.

Structure (3D structures containing this domain)

3D Structures of ChtBD1 domains in PDB

PDB code	Title
1ehd	CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ ISOLECTIN VI
1ehh	CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ ISOLECTIN VI COMPLEX WITH TRI-N-ACETYLCHITOTRIOSE
1eis	UDA UNCOMPLEXED FORM. CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ, A SUPERANTIGEN PRESENTED BY MHC MOLECULES OF CLASS I AND CLASS II
1en2	UDA TETRASACCHARIDE COMPLEX. CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ, A SUPERANTIGEN PRESENTED BY MHC MOLECULES OF CLASS I AND CLASS II
1enm	UDA TRISACCHARIDE COMPLEX. CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ, A SUPERANTIGEN PRESENTED BY MHC MOLECULES OF CLASS I AND CLASS II
1hev	HEVEIN: THE NMR ASSIGNMENT AND AN ASSESSMENT OF SOLUTION-STATE FOLDING FOR THE AGGLUTININ-TOXIN MOTIF
1iqb	Crystal Structure of Urtica dioica Agglutinin Isolectin I
1k7t	Crystal Structure Analysis of crosslinked-WGA3/GlcNAcbeta1,6Gal complex
1k7u	Crystal Structure Analysis of crosslinked-WGA3/GlcNAcbeta1,4GlcNAc complex
1k7v	Crystal Structure Analysis of crosslinked-WGA3/GlcNAcbeta1,6Galbeta1,4Glc
1mmc	1H NMR STUDY OF THE SOLUTION STRUCTURE OF AC-AMP2
1p9g	Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Ecommia ulmoides Oliver at atomic resolution
1p9z	The Solution Structure of Antifungal Peptide Distinct With a Five-disulfide Motif from Eucommia ulmoides Oliver
1q9b	CRYSTAL STRUCTURE ANALYSIS OF Hev b 6.02 (HEVEIN) AT 1.5 ANGSTROMS RESOLUTION
1t0w	25 NMR structures of Truncated Hevein of 32 aa (Hevein-32) complex with N,N,N-triacetylglucosamina
1uha	Crystal Structure of Pokeweed Lectin-D2
1ulk	Crystal Structure of Pokeweed Lectin-C
1ulm	Crystal Structure of Pokeweed Lectin-D2 complexed with tri-N-acetylchitotriose
1uln	Crystal Structure of Pokeweed Lectin-D1
1wgc	2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES
1wgt	X-RAY STRUCTURE OF WHEAT GERM AGGLUTININ ISOLECTIN 3
1wkx	Crystal Structure of a Hev b 6.02 Isoallergen
1znt	18 NMR structures of AcAMP2-Like Peptide with non Natural Fluoroaromatic Residue (AcAMP2F18Pff/Y20Pff) complex with N,N,N-triacetylchitotriose
1zuv	24 NMR structures of AcAMP2-Like Peptide with Phenylalanine 18 mutated to Tryptophan
1zwu	30 NMR structures of AcAMP2-like peptide with non natural beta-(2-naphthyl)-alanine residue.
2cwg	CRYSTALLOGRAPHIC REFINEMENT AND STRUCTURE ANALYSIS OF THE COMPLEX OF WHEAT GERM AGGLUTININ WITH A BIVALENT SIALOGLYCOPEPTIDE FROM GLYCOPHORIN A
2dkv	Crystal structure of class I chitinase from Oryza sativa L. japonica
2kus	Spatial structure of Antimicrobial Peptide Sm-AMP-1.1a
2lb7	Hevein-type Antifungal Peptide with a Unique 10-Cysteine Motif
2n1s	2N1S
2uvo	High Resolution Crystal Structure of Wheat Germ Agglutinin in Complex with N-Acetyl-D-Glucosamine
2wgc	2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES
2x3t	Glutaraldehyde-crosslinked wheat germ agglutinin isolectin 1 crystal soaked with a synthetic glycopeptide
2x52	CRYSTAL STRUCTURE OF WHEAT GERM AGGLUTININ ISOLECTIN 3 IN COMPLEX WITH A SYNTHETIC DIVALENT CARBOHYDRATE LIGAND
3iwr	Crystal structure of class I chitinase from Oryza sativa L. japonica
4aml	CRYSTAL STRUCTURE OF WHEAT GERM AGGLUTININ ISOLECTIN 1 IN COMPLEX WITH GLYCOSYLURETHAN
4mpi	4MPI
4wp4	4WP4
4z8i	4Z8I
4zxm	4ZXM
7wga	2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES
9wga	2.2 ANGSTROMS RESOLUTION STRUCTURE ANALYSIS OF TWO REFINED N-ACETYLNEURAMINYLLACTOSE-WHEAT GERM AGGLUTININ ISOLECTIN COMPLEXES

Links (links to other resources describing this domain)

• INTERPRO: IPR001002
• PFAM: chitin_binding
• PROSITE: CHITIN_BINDING