EKR

EKR

Domain of unknown function
SMART ACC:SM000890
Description:EKR is a short, 33 residue, domain found in bacterial and some lower eukaryotic species which lies between a POR (pyruvate ferredoxin/flavodoxin oxidoreductase) and the 4Fe-4S binding domain Fer4. It contains a characteristic EKR sequence motif. The exact function of this domain is not known.
InterPro ACC:IPR019456
InterPro abstract:

EKR is a short, 33 residue, domain found in bacterial and some lower eukaryotic species which lies between a POR (pyruvate ferredoxin/flavodoxin oxidoreductase) domain ( IPR019752 ) and the 4Fe-4S binding domain ( IPR017896 ). … expand

GO function:oxidoreductase activity, acting on the aldehyde or oxo group of donors (GO:0016903)
Family alignment:View the Family alignment or the Alignment consensus sequence
There are 4 864 EKR domains in 4 864 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing EKR domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing EKR domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:Metabolic

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a EKR domain which could be assigned to a KEGG orthologous group, and not all proteins containing EKR domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

3D structures in PDB containing this domain

Links to other resources describing this domain

PfamEKR
InterProIPR019456