EPEND

EPEND

Ependymins
SMART ACC:SM000026
Description: Ependymins are the predominant proteins in the cerebrospinal fluid (CSF) of teleost fish. They have been implicated in the neurochemistry of memory and neuronal regeneration. They are glycoproteins of about 200 amino acids that can bind calcium. Four cysteines are conserved that probably form disulfide bonds.
InterPro ACC:IPR001299
InterPro abstract:

Ependymins are secretory proteins found predominantly in the cerebrospinal fluid of teleost fish [ PUBMED:1831964 PUBMED:8350351 ]. A bound form of the glycoproteins is associated with the extracellular matrix, probably with collagen fibrils … expand

GO process:cell-matrix adhesion (GO:0007160)
GO component:extracellular region (GO:0005576)
GO function:calcium ion binding (GO:0005509)
Family alignment:View the Family alignment or the Alignment consensus sequence
There are 92 EPEND domains in 91 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing EPEND domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing EPEND domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a EPEND domain which could be assigned to a KEGG orthologous group, and not all proteins containing EPEND domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

KEGG orthologous groups

3D structures in PDB containing this domain

Links to other resources describing this domain

InterProIPR001299
PROSITEPS00899