 FBAF-box associated region | |
|---|---|
| SMART ACC: | SM001198 |
| Description: | Members of this family are associated with F-box domains, hence the name FBA. This domain is probably involved in binding other proteins that will be targeted for ubiquitination. Q9UK22 is involved in binding to N-glycosylated proteins. |
| InterPro ACC: | IPR007397 |
| InterPro abstract: | F-box proteins have a bipartite structure: they contain a carboxy-terminaldomain that interacts with substrates and a 42-48 amino-acid F-box domain which binds to the protein Skp1. A subset of F-box proteins ischaracterised by a ~180-residue carboxy-terminal region, which has been calledthe F-box-associated (FBA) domain [ PUBMED:10531037 … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 891 FBA domains in 1 854 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing FBA domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing FBA domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Interaction (with the environment) |
|---|
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a FBA domain which could be assigned to a KEGG orthologous group, and not all proteins containing FBA domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.