Fungal_trans Fungal specific transcription factor domain
SMART ACC:	SM000906
Description:	This domain is found in a number of fungal transcription factors including transcriptional activator xlnR, yeast regulatory protein GAL4, and other transcription proteins regulating a variety of cellular and metabolic processes.
InterPro ACC:	IPR007219
InterPro abstract:	This domain is present in the large family of fungal zinc cluster transcription factors that contain an N-terminal GAL4-like C6 zinc binuclear cluster DNA-binding domain ( IPR001138 ) [ PUBMED:16959962 PUBMED:19686338 … expand This domain is present in the large family of fungal zinc cluster transcription factors that contain an N-terminal GAL4-like C6 zinc binuclear cluster DNA-binding domain ( IPR001138 ) [ PUBMED:16959962 PUBMED:19686338 ], including Xylanolytic transcriptional activator (XnlR) and related transcriptional factors. It has been suggested that this region plays a regulatory role and it is between the DNA-binding domain and the C-terminal acidic region. XlnR is involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose [ PUBMED:18420433 PUBMED:21484208 ]. collapse
GO process:	DNA-templated transcription (GO:0006351)
GO function:	DNA binding (GO:0003677), zinc ion binding (GO:0008270)
Family alignment:	View the Family alignment or the Alignment consensus sequence
There are 50 092 Fungal_trans domains in 49 938 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing Fungal_trans domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Fungal_trans domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

Predicted cellular role

Cellular role:	Transcription

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Fungal_trans domain which could be assigned to a KEGG orthologous group, and not all proteins containing Fungal_trans domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Links to other resources describing this domain

Pfam	Fungal_trans
InterPro	IPR007219