 GAGE | |
|---|---|
| SMART ACC: | SM001379 |
| Description: | This family consists of several GAGE and XAGE proteins which are found exclusively in humans. The function of this family is unknown although they have been implicated in human cancers (PMID:11992404) |
| InterPro ACC: | IPR031320 |
| InterPro abstract: | This domain is found in antigens belonging to the GAGE/PAGE family. These antigents been implicated in human cancers [ PUBMED:11992404 PUBMED:10197611 ]. |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 853 GAGE domains in 833 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing GAGE domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing GAGE domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a GAGE domain which could be assigned to a KEGG orthologous group, and not all proteins containing GAGE domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.