 Gal-bind_lectinGalactoside-binding lectin | |
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| SMART ACC: | SM000908 |
| Description: | Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals (PUBMED:8124704). Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction. |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 10 779 Gal-bind_lectin domains in 7 909 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing Gal-bind_lectin domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing Gal-bind_lectin domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Metabolic |
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KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Gal-bind_lectin domain which could be assigned to a KEGG orthologous group, and not all proteins containing Gal-bind_lectin domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.
KEGG pathways
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.
KEGG orthologous groups
Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.
3D structures in PDB containing this domain
Links to other resources describing this domain
| Pfam | Gal-bind_lectin |
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