 MiltonKinesin associated protein | |
|---|---|
| SMART ACC: | SM001423 |
| Description: | This domain family is found in eukaryotes, and is typically between 143 and 173 amino acids in length. This family is a region of the protein milton. Milton recruits the heavy chain of kinesin to mitochondria to allow the motor movement function of kinesin. |
| InterPro ACC: | IPR022154 |
| InterPro abstract: | This domain can be found at the C terminus of the eukaryotic trafficking kinesin-binding proteins, including TRAK1 and TRAK2. TRAK1 binds to both kinesin-1 and dynein/dynactin, is prominently localized in axons, and is needed for normal axon outgrowth, whereas TRAK2 predominantly interacts with dynein/dynactin, is more abundantly present in dendrites, and is required for dendritic development … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 0 Milton domains in 0 proteins in SMART's NRDB database. | |
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a Milton domain which could be assigned to a KEGG orthologous group, and not all proteins containing Milton domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.