 NMUNeuromedin U | |
|---|---|
| SMART ACC: | SM000084 |
| Description: | Neuromedin U (NmU) is a vertebrate peptide which stimulates uterine smooth muscle contraction and causes selective vasoconstriction. Like most other active peptides, it is proteolytically processed from a larger precursor protein. The mature peptides are 8 (NmU-8) to 25 (NmU-25) residues long and C- terminally amidated. The sequence of the C-terminal extremity of NmU is extremely well conserved in mammals, birds and amphibians. |
| InterPro ACC: | IPR008200 |
| InterPro abstract: | Neuromedin U (NmU) [ PUBMED:3239891 PUBMED:1455013 ] is a vertebrate peptide which stimulates uterine smooth muscle contraction and causes selective vasoconstriction. Like most other active peptides, it is proteolytically processed from a larger … expand |
| GO process: | regulation of smooth muscle contraction (GO:0006940) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 312 NMU domains in 312 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing NMU domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing NMU domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Relevant references for this domain
Primary literature for the NMU domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a NMU domain which could be assigned to a KEGG orthologous group, and not all proteins containing NMU domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.