 PROFProfilin | |
|---|---|
| SMART ACC: | SM000392 |
| Description: | Binds actin monomers, membrane polyphosphoinositides and poly-L-proline. |
| InterPro ACC: | IPR005455 |
| InterPro abstract: | This entry represents the Profilin family, which are small eukaryotic proteins that have different functions. In plants, they are major allergens present in pollens [ PUBMED:21458043 ]. The majority of the Profilin family members binds to monomeric actin (G-actin) in a 1:1 ratio thus preventing the polymerisation … expand |
| GO function: | actin binding (GO:0003779) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 1 685 PROF domains in 1 683 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing PROF domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing PROF domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Relevant references for this domain
Primary literature for the PROF domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a PROF domain which could be assigned to a KEGG orthologous group, and not all proteins containing PROF domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.