 PepX_CX-Pro dipeptidyl-peptidase C-terminal non-catalytic domain | |
|---|---|
| SMART ACC: | SM000939 |
| Description: | This domain is found at the C-terminus of cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). The domain, which is a beta sandwich, is also found in serine peptidases belonging to MEROPS peptidase family S15: Xaa-Pro dipeptidyl-peptidases. Members of this entry, that are not characterised as peptidases, show extensive low-level similarity to the Xaa-Pro dipeptidyl-peptidases. |
| InterPro ACC: | IPR013736 |
| InterPro abstract: | This domain is found at the C terminus of cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). The domain, which is a β sandwich, is also found in serine peptidases belonging to MEROPS peptidase family S15: Xaa-Pro dipeptidyl-peptidases. Members of this entry, that are not characterised as peptidases, show extensive … expand |
| GO function: | dipeptidyl-peptidase activity (GO:0008239) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 15 789 PepX_C domains in 15 787 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing PepX_C domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing PepX_C domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Metabolic |
|---|
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a PepX_C domain which could be assigned to a KEGG orthologous group, and not all proteins containing PepX_C domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.