WR1

WR1

Worm-specific repeat type 1
SMART ACC:SM000289
Description:Worm-specific repeat type 1. Cysteine-rich domain apparently unique (so far) to C. elegans. Often appears with KU domains. About 3 dozen worm proteins contain this domain.
InterPro ACC:IPR006150
InterPro abstract:

This repeat, originally named as Worm-specific repeat type 1, is found in several Caenorhabditis elegans proteins, as well as some other eukaryotes. The region contains several conserved cysteines that probably form disulphide bridges and is often found associated with kunitz domains IPR002223 that may function … expand

Family alignment:View the Family alignment or the Alignment consensus sequence
There are 14 923 WR1 domains in 4 256 proteins in SMART's NRDB database.

Taxonomic distribution of proteins containing WR1 domains

The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing WR1 domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.

KEGG pathways involving proteins which contain this domain

This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a WR1 domain which could be assigned to a KEGG orthologous group, and not all proteins containing WR1 domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.

KEGG pathways

Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

Some of these KOs are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Links to other resources describing this domain

InterProIPR006150