zf-3CxxCZinc-binding domain | |
|---|---|
| SMART ACC: | SM001328 |
| Description: | This is a family with several pairs of CxxC motifs possibly representing a multiple zinc-binding region. Only one pair of cysteines is associated with a highly conserved histidine residue. |
| InterPro ACC: | IPR027377 |
| InterPro abstract: | This is a domain with several pairs of CxxC motifs, referred to as 3CxxC-type zinc finger which is found in 3CxxC-type zinc finger proteins, such as zygote arrest protein 1 (ZAR1) and its homologues, ZAR1-like proteins, and receptor-transporting proteins 1-5 (RTP1-5). Only one pair of cysteines is associated with a highly conserved histidine residue. ZAR1 is essential for female fertility … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 2 480 zf-3CxxC domains in 2 474 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing zf-3CxxC domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing zf-3CxxC domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a zf-3CxxC domain which could be assigned to a KEGG orthologous group, and not all proteins containing zf-3CxxC domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.