The Pfam:RhoGEF domain within your query sequence starts at position 98 and ends at position 219, and its E-value is 2e-24.

IIRELIQTERDYLTDLELCLREVVQPLRSKQIDRLDVEGLFSNIESVHQISAKLLSLLEEATTDVEPAMQVIGEVFLQIKGPLEDIYKIYCYHHDEAHSVLESYEKEEELKQHLSHCLQSLK
Pfam:RhoGEF

Pfam:RhoGEF
Pfam domain

Pfam ACC: