|SMART accession number:||SM00996|
|Interpro abstract (IPR000043):|
Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase, EC 188.8.131.52) (AdoHcyase) is an enzyme of the activated methyl cycle, responsible for the reversible hydration of S-adenosyl-L-homocysteine into adenosine and homocysteine. This enzyme is ubiquitous, highly conserved, and may play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. AdoHcyase requires NAD+ as a cofactor and contains a central glycine-rich region which is thought to be involved in NAD-binding.
|GO process:||one-carbon metabolic process (GO:0006730)|
|GO function:||adenosylhomocysteinase activity (GO:0004013)|
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