DIM1

Mitosis protein DIM1
DIM1
SMART accession number:SM01410
Description: -
Interpro abstract (IPR004123):

This entry represents fission yeast Dim1 and its homologues, including Dib1 from budding yeasts, YLS8 from plants and TXNL4 from animals. Dim1 was originally identified as a mitosis protein [ (PUBMED:9182666) ]. Later, it was found to interact with spliceosome component Prp6, which is involved in pre-mRNA splicing [ (PUBMED:11054566) ]. Dim1 may act at the level of mRNA, which impacts the functioning of the APC/C, a critical complex in controlling mitotic progression [ (PUBMED:15755920) ].

It's worth noting that although the Dim proteins exhibit a thioredoxin-like fold, they lack the disulfide bond required for the thioredoxin redox activity [ (PUBMED:17558560) ].

GO process:mRNA splicing, via spliceosome (GO:0000398)
GO component:U4/U6 x U5 tri-snRNP complex (GO:0046540)
Family alignment:
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There are 0 DIM1 domains in 0 proteins in SMART's nrdb database.

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