Alternative splicing regulator
SMART accession number:SM01141
Description: This entry represents the conserved N-terminal region of SWAP (suppressor-of-white-apricot protein) proteins. This region contains two highly conserved motifs, viz: DRY and EERY, which appear to be the sites for alternative splicing of exons 2 and 3 of the SWAP mRNA [(PUBMED:8206918)]. These proteins are thus thought to be involved in auto-regulation of pre-mRNA splicing. Most family members are associated with two SWAP (Surp) domains SM00648 and an Arginine- serine-rich binding region towards the C-terminus.
Family alignment:
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There are 521 DRY_EERY domains in 521 proteins in SMART's nrdb database.

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