Dynein_lightDynein light chain type 1
|SMART accession number:||SM01375|
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- Evolution (species in which this domain is found)
Taxonomic distribution of proteins containing Dynein_light domain.
This tree includes only several representative species. The complete taxonomic breakdown of all proteins with Dynein_light domain is also avaliable.
Click on the protein counts, or double click on taxonomic names to display all proteins containing Dynein_light domain in the selected taxonomic class.
- Literature (relevant references for this domain)
Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.
- Tochio H, Ohki S, Zhang Q, Li M, Zhang M
- Solution structure of a protein inhibitor of neuronal nitric oxide synthase.
- Nat Struct Biol. 1998; 5: 965-9
- Display abstract
The structure of the neuronal nitric oxide synthase inhibitory protein, PIN(protein inhibitor of nNOS), has been determined by NMR spectroscopy. TwoN-terminal antiparallel alpha-helices pack against a four-stranded antiparallelbeta-sheet in the C-terminal region of the protein, forming a two-layeralpha/beta plait. The three dimensional structure of PIN resembles the fold ofthe B-chain of aspartylglucosaminidase. A non-prolyl cis peptide bond was foundbetween Pro 52 and Thr 53 of the protein. PIN has a large solvent-exposedhydrophobic surface that contains a cavity and is rimmed with positive charges.This surface may serve as the primary target-binding region for thismulti-functional regulatory protein.
- Structure (3D structures containing this domain)
3D Structures of Dynein_light domains in PDB
PDB code Main view Title 1cmi STRUCTURE OF THE HUMAN PIN/LC8 DIMER WITH A BOUND PEPTIDE 1f3c REFINED SOLUTION STRUCTURE OF 8KDA DYNEIN LIGHT CHAIN (DLC8) 1f95 SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND BIM PEPTIDE COMPLEX 1f96 SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND NNOS PEPTIDE COMPLEX 1pwj Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly 1pwk Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly 1re6 Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands 1rhw The solution structure of the pH-induced monomer of dynein light chain LC8 from Drosophila 1yo3 1.65 Angstrom Structure of the Dynein Light Chain 1 from Plasmodium falciparum 2p2t Crystal structure of dynein light chain LC8 bound to residues 123-138 of intermediate chain IC74 2pg1 Structural analysis of a cytoplasmic dynein Light Chain-Intermediate Chain complex 2xqq Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide (Ac-SRGTQTE). 3bri Crystal Structure of apo-LC8 3brl Crystal Structure of LC8 S88E / Swa 3dvh LC8 Point mutant K36P 3dvp Pak1 peptide bound LC8 3dvt Biochemical and structural characterization of the PAK1- LC8 interaction 3e2b Crystal structure of Dynein Light chain LC8 in complex with a peptide derived from Swallow 3fm7 Quaternary Structure of Drosophila melanogaster IC/Tctex-1/LC8; Allosteric Interactions of Dynein Light Chains with Dynein Intermediate Chain 3glw Quaternary Structure of Drosophila melanogaster IC/Tctex-1/LC8; Allosteric Interactions of Dynein Light Chains with Dynein Intermediate Chain 3p8m Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide dimerized by leucine zipper 3rjs Crystal structure of Dynein Light Chain 8a (DLC8) from Toxoplasma gondii at 1.5 A resolution 3zke Structure of LC8 in complex with Nek9 peptide 3zkf Structure of LC8 in complex with Nek9 phosphopeptide 4ds1 The Structure of a Yeast Dyn2-Nup159 Complex and the Molecular Basis for the Dynein Light Chain - Nuclear Pore Interaction 4ht6 The Structure of a Yeast Dynein Dyn2-Pac11 Complex and Effect on Single Molecule Dynein Motor Activity
- Links (links to other resources describing this domain)