The domain within your query sequence starts at position 254 and ends at position 439; the E-value for the ICA69 domain shown below is 2.7e-64.

PYDFLALKRLQDTPGNLTADCTEGQTEGSCLTTDLNKVALSEEEEEERFEREPAVARALP
RDSLEGDDFEKEFSFLNSLLSPTSSSASEFTQECQPACGSPCTGLTSQEPSVGPGSLTSS
SQFLPSQLFDLGLHADGAFNIWASQKRSEHSDTLPVPSQHPKKLKYLGPLSNPDAIGHSD
DELLNA

ICA69

Islet cell autoantigen ICA69, C-terminal domain
ICA69
SMART accession number:SM01237
Description: This family includes a 69 kD protein which has been identified as an islet cell autoantigen in type I diabetes mellitus (PMID:8975715). Its precise function is unknown.
Interpro abstract (IPR006723): This entry represents a C-terminal domain found in islet cell autoantigen Ica1. Ica1 has been identified as an islet cell autoantigen in type I diabetes mellitus [(PUBMED:8975715)]. Its precise function is unknown, though it may play a role in neurotransmitter secretion [(PUBMED:11029035)].
Family alignment:
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There are 1020 ICA69 domains in 1020 proteins in SMART's nrdb database.

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