LYZ1Alpha-lactalbumin / lysozyme C |
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SMART accession number: | SM00263 |
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Description: | - |
Interpro abstract (IPR001916): | O-Glycosyl hydrolases ( EC 3.2.1. ) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [ (PUBMED:7624375) (PUBMED:8535779) ]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website. Glycoside hydrolase family 22 comprises enzymes with two known activities; lysozyme type C ( EC 3.2.1.17 ) (also known as 1, 4-beta-N-acetylmuramidase or LYZ) and alpha-lactalbumins (also known as lactose synthase B protein or LA). Asp and/or the carbonyl oxygen of the C-2 acetamido group of the substrate acts as the catalytic nucleophile/base. Alpha-lactalbumin [ (PUBMED:6715332) (PUBMED:3104032) ] is a milk protein that acts as the regulatory subunit of lactose synthetase, acting to promote the conversion of galactosyltransferase to lactose synthase, which is essential for milk production. In the mammary gland, alpha-lactalbumin changes the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. Lysozymes ( EC 3.2.1.17 ) act as bacteriolytic enzymes by hydrolyzing the beta(1->4) bonds between N-acetylglucosamine and N-acetylmuramic acid in the peptidoglycan of prokaryotic cell walls. It has also been recruited for a digestive role in certain ruminants and colobine monkeys [ (PUBMED:2738070) ]. There are at least five different classes of lysozymes [ (PUBMED:3148618) ]: C (chicken type), G (goose type), phage-type (T4), fungi (Chalaropsis), and bacterial (Bacillus subtilis). There are few similarities in the sequences of the different types of lysozymes. Lysozyme type C and alpha-lactalbumin are similar both in terms of primary sequence and structure, and probably evolved from a common ancestral protein [ (PUBMED:2731545) ]. Around 35 to 40% of the residues are conserved in both proteins as well as the positions of the four disulphide bonds. There is, however, no similarity in function. Another significant difference between the two enzymes is that all lactalbumins have the ability to bind calcium [ (PUBMED:3785375) ], while this property is restricted to only a few lysozymes [ (PUBMED:3666156) ]. The binding site was deduced using high resolution X-ray structure analysis and was shown to consist of three aspartic acid residues. It was first suggested that calcium bound to lactalbumin stabilised the structure, but recently it has been claimed that calcium controls the release of lactalbumin from the golgi membrane and that the pattern of ion binding may also affect the catalytic properties of the lactose synthetase complex. Sperm acrosome membrane-associated protein 3 (SPACA3) is involved in fertilization, probably during the sperm-egg membrane fusion, but despite being homologous to lysosome has no detectable bacteriolytic activity [ (PUBMED:12606493) ]. |
Family alignment: |
There are 3162 LYZ1 domains in 2862 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
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Taxonomic distribution of proteins containing LYZ1 domain.
This tree includes only several representative species. The complete taxonomic breakdown of all proteins with LYZ1 domain is also avaliable.
Click on the protein counts, or double click on taxonomic names to display all proteins containing LYZ1 domain in the selected taxonomic class.
- Disease (disease genes where sequence variants are found in this domain)
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SwissProt sequences and OMIM curated human diseases associated with missense mutations within the LYZ1 domain.
Protein Disease Lysozyme C (P61626) (SMART) OMIM:153450: Amyloidosis, renal
OMIM:105200: - Metabolism (metabolic pathways involving proteins which contain this domain)
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Click the image to view the interactive version of the map in iPath% proteins involved KEGG pathway ID Description 77.78 map00052 Galactose metabolism 22.22 map00500 Starch and sucrose metabolism This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with LYZ1 domain which could be assigned to a KEGG orthologous group, and not all proteins containing LYZ1 domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.
- Structure (3D structures containing this domain)
3D Structures of LYZ1 domains in PDB
PDB code Main view Title 132l STRUCTURAL CONSEQUENCES OF REDUCTIVE METHYLATION OF LYSINE RESIDUES IN HEN EGG WHITE LYSOZYME: AN X-RAY ANALYSIS AT 1.8 ANGSTROMS RESOLUTION 133l ROLE OF ARG 115 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME. X-RAY STRUCTURE OF HIS 115 AND GLU 115 MUTANTS 134l ROLE OF ARG 115 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME. X-RAY STRUCTURE OF HIS 115 AND GLU 115 MUTANTS 135l X-RAY STRUCTURE OF MONOCLINIC TURKEY EGG LYSOZYME AT 1.3 ANGSTROMS RESOLUTION 193l THE 1.33 A STRUCTURE OF TETRAGONAL HEN EGG WHITE LYSOZYME 194l THE 1.40 A STRUCTURE OF SPACEHAB-01 HEN EGG WHITE LYSOZYME 1a2y HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3 1a4v ALPHA-LACTALBUMIN 1aki THE STRUCTURE OF THE ORTHORHOMBIC FORM OF HEN EGG-WHITE LYSOZYME AT 1.5 ANGSTROMS RESOLUTION 1alc REFINED STRUCTURE OF BABOON ALPHA-LACTALBUMIN AT 1.7 ANGSTROMS RESOLUTION. COMPARISON WITH C-TYPE LYSOZYME 1at5 HEN EGG WHITE LYSOZYME WITH A SUCCINIMIDE RESIDUE 1at6 HEN EGG WHITE LYSOZYME WITH A ISOASPARTATE RESIDUE 1azf CHICKEN EGG WHITE LYSOZYME CRYSTAL GROWN IN BROMIDE SOLUTION 1b0d Structural effects of monovalent anions on polymorphic lysozyme crystals 1b2k Structural effects of monovalent anions on polymorphic lysozyme crystals 1b5u CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME: CALORIMETRY AND X-RAY ANALYSIS OF SIX SER->ALA MUTANT 1b5v CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME: CALORIMETRY AND X-RAY ANALYSIS OF SIX SER->ALA MUTANTS 1b5w CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME: CALORIMETRY AND X-RAY ANALYSIS OF SIX SER->ALA MUTANTS 1b5x Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and x-ray analysis of six ser->ala mutants 1b5y CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME: CALORIMETRY AND X-RAY ANALYSIS OF SIX SER->ALA MUTANTS 1b5z CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME: CALORIMETRY AND X-RAY ANALYSIS OF SIX SER->ALA MUTANTS 1b7l VERIFICATION OF SPMP USING MUTANT HUMAN LYSOZYMES 1b7m VERIFICATION OF SPMP USING MUTANT HUMAN LYSOZYMES 1b7n VERIFICATION OF SPMP USING MUTANT HUMAN LYSOZYMES 1b7o VERIFICATION OF SPMP USING MUTANT HUMAN LYSOZYMES 1b7p VERIFICATION OF SPMP USING MUTANT HUMAN LYSOZYMES 1b7q VERIFICATION OF SPMP USING MUTANT HUMAN LYSOZYMES 1b7r VERIFICATION OF SPMP USING MUTANT HUMAN LYSOZYMES 1b7s VERIFICATION OF SPMP USING MUTANT HUMAN LYSOZYMES 1b9o HUMAN ALPHA-LACTALBUMIN, LOW TEMPERATURE FORM 1bb3 HUMAN LYSOZYME MUTANT A96L 1bb4 HUMAN LYSOZYME DOUBLE MUTANT A96L, W109H 1bb5 HUMAN LYSOZYME MUTANT A96L COMPLEXED WITH CHITOTRIOSE 1bb6 LYSOZYME COMPLEX WITH 4-METHYL-UMBELLIFERYL CHITOTRIOSE 1bb7 LYSOZYME COMPLEX WITH 4-METHYL-UMBELLIFERYL CHITOBIOSE 1bgi ORTHORHOMBIC LYSOZYME CRYSTALLIZED AT HIGH TEMPERATURE (310K) 1bhz LOW TEMPERATURE MIDDLE RESOLUTION STRUCTURE OF HEN EGG WHITE LYSOZYME FROM MASC DATA 1bql STRUCTURE OF AN ANTI-HEL FAB FRAGMENT COMPLEXED WITH BOBWHITE QUAIL LYSOZYME 1bvk HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME 1bvx THE 1.8 A STRUCTURE OF GEL GROWN TETRAGONAL HEN EGG WHITE LYSOZYME 1bwh THE 1.8 A STRUCTURE OF GROUND CONTROL GROWN TETRAGONAL HEN EGG WHITE LYSOZYME 1bwi THE 1.8 A STRUCTURE OF MICROBATCH OIL DROP GROWN TETRAGONAL HEN EGG WHITE LYSOZYME 1bwj THE 1.8 A STRUCTURE OF MICROGRAVITY GROWN TETRAGONAL HEN EGG WHITE LYSOZYME 1c08 CRYSTAL STRUCTURE OF HYHEL-10 FV-HEN LYSOZYME COMPLEX 1c10 CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF XENON (8 BAR) 1c43 MUTANT HUMAN LYSOZYME WITH FOREIGN N-TERMINAL RESIDUES 1c45 MUTANT HUMAN LYSOZYME WITH FOREIGN N-TERMINAL RESIDUES 1c46 MUTANT HUMAN LYSOZYME WITH FOREIGN N-TERMINAL RESIDUES 1c7p CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME WITH FOUR EXTRA RESIDUES (EAEA) AT THE N-TERMINAL 1cj6 T11A MUTANT HUMAN LYSOZYME 1cj7 T11V MUTANT HUMAN LYSOZYME 1cj8 T40A MUTANT HUMAN LYSOZYME 1cj9 T40V MUTANT HUMAN LYSOZYME 1ckc T43A MUTANT HUMAN LYSOZYME 1ckd T43V MUTANT HUMAN LYSOZYME 1ckf T52A MUTANT HUMAN LYSOZYME 1ckg T52V MUTANT HUMAN LYSOZYME 1ckh T70V MUTANT HUMAN LYSOZYME 1d6p HUMAN LYSOZYME L63 MUTANT LABELLED WITH 2',3'-EPOXYPROPYL N,N'-DIACETYLCHITOBIOSE 1d6q HUMAN LYSOZYME E102 MUTANT LABELLED WITH 2',3'-EPOXYPROPYL GLYCOSIDE OF N-ACETYLLACTOSAMINE 1di3 ROLE OF AMINO ACID RESIDUES AT TURNS IN THE CONFORMATIONAL STABILITY AND FOLDING OF HUMAN LYSOZYME 1di4 ROLE OF AMINO ACID RESIDUES AT TURNS IN THE CONFORMATIONAL STABILITY AND FOLDING OF HUMAN LYSOZYME 1di5 ROLE OF AMINO ACID RESIDUES AT TURNS IN THE CONFORMATIONAL STABILITY AND FOLDING OF HUMAN LYSOZYME 1dkj BOBWHITE QUAIL LYSOZYME 1dkk BOBWHITE QUAIL LYSOZYME WITH NITRATE 1dpw STRUCTURE OF HEN EGG-WHITE LYSOZYME IN COMPLEX WITH MPD 1dpx STRUCTURE OF HEN EGG-WHITE LYSOZYME 1dqj CRYSTAL STRUCTURE OF THE ANTI-LYSOZYME ANTIBODY HYHEL-63 COMPLEXED WITH HEN EGG WHITE LYSOZYME 1dzb Crystal structure of phage library-derived single-chain Fv fragment 1F9 in complex with turkey egg-white lysozyme 1e8l NMR solution structure of hen lysozyme 1el1 X-RAY CRYSTAL STRUCTURE ANALYSIS OF CANINE MILK LYSOZYME (HOLO-TYPE) 1eq4 CRYSTAL STRUCTURES OF SALT BRIDGE MUTANTS OF HUMAN LYSOZYME 1eq5 CRYSTAL STRUCTURES OF SALT BRIDGE MUTANTS OF HUMAN LYSOZYME 1eqe CRYSTAL STRUCTURES OF SALT BRIDGE MUTANTS OF HUMAN LYSOZYME 1f0w CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 6.5 1f10 CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 6.5 AT 88% RELATIVE HUMIDITY 1f6r CRYSTAL STRUCTURE OF APO-BOVINE ALPHA-LACTALBUMIN 1f6s CRYSTAL STRUCTURE OF BOVINE ALPHA-LACTALBUMIN 1fbi CRYSTAL STRUCTURE OF A CROSS-REACTION COMPLEX BETWEEN FAB F9.13.7 AND GUINEA-FOWL LYSOZYME 1fdl CRYSTALLOGRAPHIC REFINEMENT OF THE THREE-DIMENSIONAL STRUCTURE OF THE FAB D1.3-LYSOZYME COMPLEX AT 2.5-ANGSTROMS RESOLUTION 1fkq RECOMBINANT GOAT ALPHA-LACTALBUMIN T29V 1fkv RECOMBINANT GOAT ALPHA-LACTALBUMIN T29I 1flq HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE 1flu HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE 1flw HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE 1fly HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE 1fn5 HEN EGG WHITE LYSOZYME MUTANT WITH ALANINE SUBSTITUTED FOR GLYCINE 1g7h CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3(VLW92A) 1g7i CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92F) 1g7j CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92H) 1g7l CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92S) 1g7m CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V) 1gay CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gaz Crystal Structure of Mutant Human Lysozyme Substituted at the Surface Positions 1gb0 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gb2 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gb3 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gb5 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gb6 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gb7 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gb8 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gb9 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gbo CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gbw CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gbx CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gby CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gbz CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gd6 STRUCTURE OF THE BOMBYX MORI LYSOZYME 1gdw CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT LEFT-HANDED HELICAL POSITIONS 1gdx CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT LEFT-HANDED HELICAL POSITIONS 1ge0 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT LEFT-HANDED HELICAL POSITIONS 1ge1 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT LEFT-HANDED HELICAL POSITIONS 1ge2 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT LEFT-HANDED HELICAL POSITIONS 1ge3 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT LEFT-HANDED HELICAL POSITIONS 1ge4 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT LEFT-HANDED HELICAL POSITIONS 1gev BURIED POLAR MUTANT HUMAN LYSOZYME 1gez BURIED POLAR MUTANT HUMAN LYSOZYME 1gf0 BURIED POLAR MUTANT HUMAN LYSOZYME 1gf3 BURIED POLAR MUTANT HUMAN LYSOZYME 1gf4 BURIED POLAR MUTANT HUMAN LYSOZYME 1gf5 BURIED POLAR MUTANT HUMAN LYSOZYME 1gf6 BURIED POLAR MUTANT HUMAN LYSOZYME 1gf7 BURIED POLAR MUTANT HUMAN LYSOZYME 1gf8 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gf9 CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gfa CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gfe CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gfg CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gfh CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gfj CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gfk CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gfr CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gft CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gfu CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1gfv CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1ghl THE THREE-DIMENSIONAL STRUCTURE OF PHEASANT AND GUINEA-FOWL EGG LYSOZYMES 1gpq Structure of ivy complexed with its target, HEWL 1gwd Tri-iodide derivative of hen egg-white lysozyme 1gxv Solution structure of lysozyme at low and high pressure 1gxx Solution structure of lysozyme at low and high pressure 1h6m Covalent glycosyl-enzyme intermediate of hen egg white lysozyme 1h87 Gadolinium derivative of tetragonal Hen Egg-White Lysozyme at 1.7 A resolution 1hc0 structure of lysozyme with periodate 1hel STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME 1hem STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME 1hen STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME 1heo STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME 1hep STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME 1heq STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME 1her STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME 1hew REFINEMENT OF AN ENZYME COMPLEX WITH INHIBITOR BOUND AT PARTIAL OCCUPANCY. HEN EGG-WHITE LYSOZYME AND TRI-N-ACETYLCHITOTRIOSE AT 1.75 ANGSTROMS RESOLUTION 1hf4 STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON POLYMORPHIC LYSOZYME CRYSTALS 1hfx ALPHA-LACTALBUMIN 1hfy ALPHA-LACTALBUMIN 1hfz ALPHA-LACTALBUMIN 1hhl THE THREE-DIMENSIONAL STRUCTURE OF PHEASANT AND GUINEA-FOWL EGG LYSOZYMES 1hmk RECOMBINANT GOAT ALPHA-LACTALBUMIN 1hml ALPHA_LACTALBUMIN POSSESSES A DISTINCT ZINC BINDING SITE 1hnl CRYSTAL STRUCTURE OF A GLUTATHIONYLATED HUMAN LYSOZYME: A FOLDING INTERMEDIATE MIMIC IN THE FORMATION OF A DISULFIDE BOND 1hsw LYSOZYME (MUCOPEPTIDE N-ACETYLMURAMYL HYDROLASE) 1hsx LYSOZYME GROWN AT BASIC PH AND ITS LOW HUMIDITY VARIANT 1i1z MUTANT HUMAN LYSOZYME (Q86D) 1i20 MUTANT HUMAN LYSOZYME (A92D) 1i22 MUTANT HUMAN LYSOZYME (A83K/Q86D/A92D) 1i56 SOLUTION STRUCTURE OF CA2+-BOUND STATE OF CANINE MILK LYSOZYME 1ic4 CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX 1ic5 CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD99A)-HEN LYSOZYME COMPLEX 1ic7 CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A99A)-HEN LYSOZYME COMPLEX 1iee STRUCTURE OF TETRAGONAL HEN EGG WHITE LYSOZYME AT 0.94 A FROM CRYSTALS GROWN BY THE COUNTER-DIFFUSION METHOD 1iiz Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta 1inu CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 1io5 HYDROGEN AND HYDRATION OF HEN EGG-WHITE LYSOZYME DETERMINED BY NEUTRON DIFFRACTION 1ioc CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME, EAEA-I56T 1ioq STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION 1ior STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION 1ios STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION 1iot STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION 1ip1 G37A HUMAN LYSOZYME 1ip2 G48A HUMAN LYSOZYME 1ip3 G68A HUMAN LYSOZYME 1ip4 G72A HUMAN LYSOZYME 1ip5 G105A HUMAN LYSOZYME 1ip6 G127A HUMAN LYSOZYME 1ip7 G129A HUMAN LYSOZYME 1ir7 IM mutant of lysozyme 1ir8 IM mutant of lysozyme 1ir9 IM mutant of lysozyme 1ivm Solution structure of mouse lysozyme M 1iwt Crystal Structure Analysis of Human lysozyme at 113K. 1iwu Crystal Structure Analysis of Human lysozyme at 127K. 1iwv Crystal Structure Analysis of Human lysozyme at 147K. 1iww Crystal Structure Analysis of Human lysozyme at 152K. 1iwx Crystal Structure Analysis of Human lysozyme at 161K. 1iwy Crystal Structure Analysis of Human lysozyme at 170K. 1iwz Crystal Structure Analysis of Human lysozyme at 178K. 1ix0 I59A-3SS human lysozyme 1iy3 Solution Structure of the Human lysozyme at 4 degree C 1iy4 Solution structure of the human lysozyme at 35 degree C 1j1o Crystal Structure of HyHEL-10 Fv mutant LY50F complexed with hen egg white lysozyme 1j1p Crystal structure of HyHEL-10 Fv mutant LS91A complexed with hen egg white lysozyme 1j1x Crystal Structure of HyHEL-10 Fv mutant LS93A complexed with hen egg white lysozyme 1ja2 BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN EGG LYSOZYME: A POWDER DIFFRACTION STUDY 1ja4 BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN EGG LYSOZYME: A POWDER DIFFRACTION STUDY 1ja6 BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN EGG LYSOZYME: A POWDER DIFFRACTION STUDY 1ja7 BINDING OF N-ACETYLGLUCOSAMINE TO CHICKEN EGG LYSOZYME: A POWDER DIFFRACTION STUDY 1jef TURKEY LYSOZYME COMPLEX WITH (GLCNAC)3 1jhl THREE-DIMENSIONAL STRUCTURE OF A HETEROCLITIC ANTIGEN-ANTIBODY CROSS-REACTION COMPLEX 1jis CRYSTAL STRUCTURE OF TETRAGONAL LYSOZYME GROWN AT PH 4.6 1jit CRYSTAL STRUCTURE OF TETRAGONAL LYSOZYME GROWN IN PRESENCE 30% TREHALOSE 1jiy CRYSTAL STRUCTURE OF TETRAGONAL LYSOZYME GROWN IN PRESENCE 20% SORBITOL 1jj0 CRYSTAL STRUCTURE OF TETRAGONAL LYSOZYME GROWN IN PRESENCE of 30% SUCROSE 1jj1 CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 4.6 IN PRESENCE OF 5% SORBITOL 1jj3 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6 1jka HUMAN LYSOZYME MUTANT WITH GLU 35 REPLACED BY ASP 1jkb HUMAN LYSOZYME MUTANT WITH GLU 35 REPLACED BY ALA 1jkc HUMAN LYSOZYME MUTANT WITH TRP 109 REPLACED BY PHE 1jkd HUMAN LYSOZYME MUTANT WITH TRP 109 REPLACED BY ALA 1jpo LOW TEMPERATURE ORTHORHOMBIC LYSOZYME 1jse FULL-MATRIX LEAST-SQUARES REFINEMENT OF TURKEY LYSOZYME 1jsf FULL-MATRIX LEAST-SQUARES REFINEMENT OF HUMAN LYSOZYME 1jto Degenerate interfaces in antigen-antibody complexes 1jtp Degenerate interfaces in antigen-antibody complexes 1jtt Degenerate interfaces in antigen-antibody complexes 1jug LYSOZYME FROM ECHIDNA MILK (TACHYGLOSSUS ACULEATUS) 1jwr Crystal structure of human lysozyme at 100 K 1kip FV MUTANT Y(B 32)A (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME 1kiq FV MUTANT Y(B 101)F (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME 1kir FV MUTANT Y(A 50)S (VL DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME 1kxw ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1kxx ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1kxy ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1laa X-RAY STRUCTURE OF GLU 53 HUMAN LYSOZYME 1lcn Monoclinic hen egg white lysozyme, thiocyanate complex 1lhh ROLE OF PROLINE RESIDUES IN HUMAN LYSOZYME STABILITY: A SCANNING CALORIMETRIC STUDY COMBINED WITH X-RAY STRUCTURE ANALYSIS OF PROLINE MUTANTS 1lhi ROLE OF PROLINE RESIDUES IN HUMAN LYSOZYME STABILITY: A SCANNING CALORIMETRIC STUDY COMBINED WITH X-RAY STRUCTURE ANALYSIS OF PROLINE MUTANTS 1lhj ROLE OF PROLINE RESIDUES IN HUMAN LYSOZYME STABILITY: A SCANNING CALORIMETRIC STUDY COMBINED WITH X-RAY STRUCTURE ANALYSIS OF PROLINE MUTANTS 1lhk ROLE OF PROLINE RESIDUES IN HUMAN LYSOZYME STABILITY: A SCANNING CALORIMETRIC STUDY COMBINED WITH X-RAY STRUCTURE ANALYSIS OF PROLINE MUTANTS 1lhl ROLE OF PROLINE RESIDUES IN HUMAN LYSOZYME STABILITY: A SCANNING CALORIMETRIC STUDY COMBINED WITH X-RAY STRUCTURE ANALYSIS OF PROLINE MUTANTS 1lhm THE CRYSTAL STRUCTURE OF A MUTANT LYSOZYME C77(SLASH)95A WITH INCREASED SECRETION EFFICIENCY IN YEAST 1lj3 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6 1lj4 CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN AT PH 4.6 1lje CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 10% SUCROSE 1ljf CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 10% SUCROSE 1ljg CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 5% GLYCEROL 1ljh CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 5% GLYCEROL 1lji CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE 10% SORBITOL 1ljj CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 10% TREHALOSE 1ljk CRYSTAL STRUCTURE OF MONOCLINIC LYSOZYME GROWN IN PRESENCE OF 15% TREHALOSE 1ljn Crystal Structure of Tuekey Egg Lysozyme Complex with Di-N-acetylchitobiose at 1.19A Resolution 1lkr MONOCLINIC HEN EGG WHITE LYSOZYME IODIDE 1lks HEN EGG WHITE LYSOZYME NITRATE 1lma PROTEIN HYDRATION AND WATER STRUCTURE: X-RAY ANALYSIS OF A CLOSELY PACKED PROTEIN CRYSTAL WITH VERY LOW SOLVENT CONTENT 1lmc THE CRYSTAL STRUCTURE OF A COMPLEX BETWEEN BULGECIN, A BACTERIAL METABOLITE, AND LYSOZYME FROM THE RAINBOW TROUT 1lmn THE REFINED CRYSTAL STRUCTURE OF LYSOZYME FROM THE RAINBOW TROUT (ONCORHYNCHUS MYKISS) 1lmo THE CRYSTAL STRUCTURES OF THREE COMPLEXES BETWEEN CHITOOLIGOSACCHARIDES AND LYSOZYME FROM THE RAINBOW TROUT 1lmp THE CRYSTAL STRUCTURES OF THREE COMPLEXES BETWEEN CHITOOLIGOSACCHARIDES AND LYSOZYME FROM THE RAINBOW TROUT 1lmq THE CRYSTAL STRUCTURES OF THREE COMPLEXES BETWEEN CHITOOLIGOSACCHARIDES AND LYSOZYME FROM THE RAINBOW TROUT 1lmt STRUCTURE OF A CONFORMATIONALLY CONSTRAINED ARG-GLY-ASP SEQUENCE INSERTED INTO HUMAN LYSOZYME 1loz AMYLOIDOGENIC VARIANT (I56T) VARIANT OF HUMAN LYSOZYME 1lpi HEW LYSOZYME: TRP...NA CATION-PI INTERACTION 1lsa THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER 1lsb THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER 1lsc THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER 1lsd THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER 1lse THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER 1lsf THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER 1lsg THREE-DIMENSIONAL STRUCTURE OF THE PLATELET INTEGRIN RECOGNITION SEGMENT OF THE FIBRINOGEN GAMMA CHAIN OBTAINED BY CARRIER PROTEIN-DRIVEN CRYSTALLIZATION 1lsm THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES 1lsn THERMAL STABILITY DETERMINANTS OF CHICKEN EGG-WHITE LYSOZYME CORE MUTANTS: HYDROPHOBICITY, PACKING VOLUME AND CONSERVED BURIED WATER MOLECULES 1lsy CRYSTAL STRUCTURE OF THE MUTANT D52S HEN EGG WHITE LYSOZYME WITH AN OLIGOSACCHARIDE PRODUCT 1lsz CRYSTAL STRUCTURE OF THE MUTANT D52S HEN EGG WHITE LYSOZYME WITH AN OLIGOSACCHARIDE PRODUCT 1lyo CROSS-LINKED LYSOZYME CRYSTAL IN NEAT WATER 1lys X-RAY STRUCTURE OF A MONOCLINIC FORM OF HEN EGG-WHITE LYSOZYME CRYSTALLIZED AT 313K. COMPARISON OF TWO INDEPENDENT MOLECULES 1lyy AMYLOIDOGENIC VARIANT (ASP67HIS) OF HUMAN LYSOZYME 1lyz REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME 1lz1 REFINEMENT OF HUMAN LYSOZYME AT 1.5 ANGSTROMS RESOLUTION. ANALYSIS OF NON-BONDED AND HYDROGEN-BOND INTERACTIONS 1lz2 CRYSTALLOGRAPHIC STUDY OF TURKEY EGG-WHITE LYSOZYME AND ITS COMPLEX WITH A DISACCHARIDE 1lz4 ENTHALPIC DESTABILIZATION OF A MUTANT HUMAN LYSOZYME LACKING A DISULFIDE BRIDGE BETWEEN CYSTEINE-77 AND CYSTEINE-95 1lz5 STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME 1lz6 STRUCTURAL AND FUNCTIONAL ANALYSES OF THE ARG-GLY-ASP SEQUENCE INTRODUCED INTO HUMAN LYSOZYME 1lz8 LYSOZYME PHASED ON ANOMALOUS SIGNAL OF SULFURS AND CHLORINES 1lz9 ANOMALOUS SIGNAL OF SOLVENT BROMINES USED FOR PHASING OF LYSOZYME 1lza DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY 1lzb DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY 1lzc DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY 1lzd DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY 1lze DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY 1lzg DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY 1lzh THE STRUCTURES OF THE MONOCLINIC AND ORTHORHOMBIC FORMS OF HEN EGG-WHITE LYSOZYME AT 6 ANGSTROMS RESOLUTION. 1lzn NEUTRON STRUCTURE OF HEN EGG-WHITE LYSOZYME 1lzr STRUCTURAL CHANGES OF THE ACTIVE SITE CLEFT AND DIFFERENT SACCHARIDE BINDING MODES IN HUMAN LYSOZYME CO-CRYSTALLIZED WITH HEXA-N-ACETYL-CHITOHEXAOSE AT PH 4.0 1lzs STRUCTURAL CHANGES OF THE ACTIVE SITE CLEFT AND DIFFERENT SACCHARIDE BINDING MODES IN HUMAN LYSOZYME CO-CRYSTALLIZED WITH HEXA-N-ACETYL-CHITOHEXAOSE AT PH 4.0 1lzt REFINEMENT OF TRICLINIC LYSOZYME 1lzy X-RAY STRUCTURE OF TURKEY EGG LYSOZYME COMPLEX WITH DI-N-ACETYLCHITOBIOSE. RECOGNITION AND BINDING OF ALPHA-ANOMERIC FORM 1mel CRYSTAL STRUCTURE OF A CAMEL SINGLE-DOMAIN VH ANTIBODY FRAGMENT IN COMPLEX WITH LYSOZYME 1mlc MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH LYSOZYME 1n4f Para-Arsanilate Derivative of Hen Egg-White Lysozyme 1nby Crystal Structure of HyHEL-63 complexed with HEL mutant K96A 1nbz Crystal Structure of HyHEL-63 complexed with HEL mutant K97A 1ndg Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme 1ndm Crystal structure of Fab fragment of antibody HyHEL-26 complexed with lysozyme 1nf5 Crystal Structure of Lactose Synthase, Complex with Glucose 1nhe Crystal structure of Lactose synthase complex with UDP 1nkh Crystal structure of Lactose synthase complex with UDP and Manganese 1nmm beta-1,4-galactosyltransferase mutant Cys342Thr complex with alpha-lactalbumin and GlcNAc 1nqi crystal structure of lactose synthase, a 1:1 complex between beta1,4-galactosyltransferase and alpha-lactalbumin in the presence of GlcNAc 1nwg BETA-1,4-GALACTOSYLTRANSFERASE COMPLEX WITH ALPHA-LACTALBUMIN AND N-BUTANOYL-GLUCOAMINE 1o23 CRYSTAL STRUCTURE OF LACTOSE SYNTHASE IN THE PRESENCE OF UDP-GLUCOSE 1op9 Complex of human lysozyme with camelid VHH HL6 antibody fragment 1oqm A 1:1 complex between alpha-lactalbumin and beta1,4-galactosyltransferase in the presence of UDP-N-acetyl-galactosamine 1oua CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE I56T MUTANT 1oub CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V100A MUTANT 1ouc CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V110A MUTANT 1oud CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V121A MUTANT 1oue CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V125A MUTANT 1ouf CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V130A MUTANT 1oug CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V2A MUTANT 1ouh CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V74A MUTANT 1oui CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V93A MUTANT 1ouj CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V99A MUTANT 1p2c crystal structure analysis of an anti-lysozyme antibody 1ps5 STRUCTURE OF THE MONOCLINIC C2 FORM OF HEN EGG-WHITE LYSOZYME AT 2.0 ANGSTROMS RESOLUTION 1pzy W314A-BETA1,4-GALACTOSYLTRANSFERASE-I COMPLEXED WITH ALPHA-LACTALBUMIN IN THE PRESENCE OF N-ACETYLGLUCOSAMINE, UDP AND MANGANESE 1qio SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE CAUSED BY INTENSE SYNCHROTRON RADIATION TO HEN EGG WHITE LYSOZYME 1qqy X-RAY CRYSTAL STRUCTURE ANALYSIS OF CANINE MILK LYSOZYME (APO-TYPE) 1qsw CRYSTAL STRUCTURE ANALYSIS OF A HUMAN LYSOZYME MUTANT W64C C65A 1qtk CRYSTAL STRUCTURE OF HEW LYSOZYME UNDER PRESSURE OF KRYPTON (55 BAR) 1rcm CRYSTAL STRUCTURE OF A UBIQUITIN-DEPENDENT DEGRADATION SUBSTRATE: A THREE-DISULFIDE FORM OF LYSOZYME 1re2 HUMAN LYSOZYME LABELLED WITH TWO 2',3'-EPOXYPROPYL BETA-GLYCOSIDE OF N-ACETYLLACTOSAMINE 1rem HUMAN LYSOZYME WITH MAN-B1,4-GLCNAC COVALENTLY ATTACHED TO ASP53 1rex NATIVE HUMAN LYSOZYME 1rey HUMAN LYSOZYME-N,N'-DIACETYLCHITOBIOSE COMPLEX 1rez HUMAN LYSOZYME-N-ACETYLLACTOSAMINE COMPLEX 1rfp ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1ri8 Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme 1rjc Crystal structure of the camelid single domain antibody cAb-Lys2 in complex with hen egg white lysozyme 1sf4 BINDING OF N,N'-DIACETYLCHITOBIOSE TO HEW LYSOZYME: A POWDER DIFFRACTION STUDY 1sf6 BINDING OF N,N',N""-TRIACETYLCHITOTRIOSE TO HEW LYSOZYME: A POWDER DIFFRACTION STUDY 1sf7 BINDING OF TETRA-N-ACETYLCHITOTETRAOSE TO HEW LYSOZYME: A POWDER DIFFRACTION STUDY 1sfb BINDING OF PENTA-N-ACETYLCHITOPENTAOSE TO HEW LYSOZYME: A POWDER DIFFRACTION STUDY 1sfg BINDING OF HEXA-N-ACETYLCHITOHEXAOSE: A POWDER DIFFRACTION STUDY 1sq2 Crystal Structure Analysis of the Nurse Shark New Antigen Receptor (NAR) Variable Domain in Complex With Lysozyme 1t3p Half-sandwich arene ruthenium(II)-enzyme complex 1t6v Crystal structure analysis of the nurse shark new antigen receptor (NAR) variable domain in complex with lysozyme 1tay DISSECTION OF THE FUNCTIONAL ROLE OF STRUCTURAL ELEMENTS OF TYROSINE-63 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME 1tby DISSECTION OF THE FUNCTIONAL ROLE OF STRUCTURAL ELEMENTS OF TYROSINE-63 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME 1tcy DISSECTION OF THE FUNCTIONAL ROLE OF STRUCTURAL ELEMENTS OF TYROSINE-63 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME 1tdy DISSECTION OF THE FUNCTIONAL ROLE OF STRUCTURAL ELEMENTS OF TYROSINE-63 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME 1tew STRUCTURE OF HEXAGONAL TURKEY EGG WHITE LYSOZYME AT 1.65 ANGSTROMS RESOLUTION 1ua6 Crystal structure of HYHEL-10 FV MUTANT SFSF complexed with HEN EGG WHITE LYSOZYME complex 1uac Crystal Structure of HYHEL-10 FV MUTANT SFSF Complexed with TURKEY WHITE LYSOZYME 1ubz Crystal structure of Glu102-mutant human lysozyme doubly labeled with 2',3'-epoxypropyl beta-glycoside of N-acetyllactosamine 1uc0 Crystal structure of wild-type hen-egg white lysozyme singly labeled with 2',3'-epoxypropyl beta-glycoside of N-acetyllactosamine 1uco HEN EGG-WHITE LYSOZYME, LOW HUMIDITY FORM 1uia ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1uib ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1uic ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1uid ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1uie ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1uif ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1uig ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1uih ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS 1uuz IVY:A NEW FAMILY OF PROTEIN 1v7s Triclinic hen lysozyme crystallized at 313K from a D2O solution 1v7t Triclinic lysozyme with low solvent content obtained by phase transition 1vat Iodine derivative of hen egg-white lysozyme 1vau Xenon derivative of hen egg-white lysozyme 1vdp The crystal structure of the monoclinic form of hen egg white lysozyme at 1.7 angstroms resolution in space 1vdq The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution 1vds The crystal structure of the tetragonal form of hen egg white lysozyme at 1.6 angstroms resolution in space 1vdt The crystal structure of the tetragonal form of hen egg white lysozyme at 1.7 angstroms resolution under basic conditions in space 1ved The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.9 angstroms resolution in space 1vfb BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION 1w08 STRUCTURE OF T70N HUMAN LYSOZYME 1w6z High Energy Tetragonal Lysozyme X-ray Structure 1wqm CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 1wqn CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 1wqo CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 1wqp CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 1wqq CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 1wqr CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 1wtm X-ray structure of HEW Lysozyme Orthorhombic Crystal formed in the Earth's magnetic field 1wtn The structure of HEW Lysozyme Orthorhombic Crystal Growth under a High Magnetic Field 1xei THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY LOW LEVELS OF HYDRATION 1xej THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY LOW LEVELS OF HYDRATION 1xek THE CRYSTAL STRUCTURES OF LYSOZYME AT VERY LOW LEVELS OF HYDRATION 1xfp Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme 1xft Synchrotron X-ray Powder Diffraction Study of Hexagonal Turkey Egg-white Lysozyme 1xgp Structure for antibody HyHEL-63 Y33A mutant complexed with hen egg lysozyme 1xgq Structure for antibody HyHEL-63 Y33V mutant complexed with hen egg lysozyme 1xgr Structure for antibody HyHEL-63 Y33I mutant complexed with hen egg lysozyme 1xgt Structure for antibody HyHEL-63 Y33L mutant complexed with hen egg lysozyme 1xgu Structure for antibody HyHEL-63 Y33F mutant complexed with hen egg lysozyme 1yam CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: CALORIMETRIC STUDIES AND X-RAY STRUCTURAL ANALYSIS OF THE FIVE ISOLEUCINE TO VALINE MUTANTS 1yan CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: CALORIMETRIC STUDIES AND X-RAY STRUCTURAL ANALYSIS OF THE FIVE ISOLEUCINE TO VALINE MUTANTS 1yao CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: CALORIMETRIC STUDIES AND X-RAY STRUCTURAL ANALYSIS OF THE FIVE ISOLEUCINE TO VALINE MUTANTS 1yap CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: CALORIMETRIC STUDIES AND X-RAY STRUCTURAL ANALYSIS OF THE FIVE ISOLEUCINE TO VALINE MUTANTS 1yaq CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: CALORIMETRIC STUDIES AND X-RAY STRUCTURAL ANALYSIS OF THE FIVE ISOLEUCINE TO VALINE MUTANTS 1yik Structure of Hen egg white lysozyme soaked with Cu-cyclam 1yil Structure of Hen egg white lysozyme soaked with Cu2-Xylylbicyclam 1ykx Effect of alcohols on protein hydration 1yky Effect of alcohols on protein hydration 1ykz Effect of alcohols on protein hydration 1yl0 Effect of alcohols on protein hydration 1yl1 Effect of alcohols on protein hydration 1yqv The crystal structure of the antibody Fab HyHEL5 complex with lysozyme at 1.7A resolution 1yro Crystal structure of beta14,-galactosyltransferase mutant ARG228Lys in complex with alpha-lactalbumin in the presence of UDP-galactose and Mn 1z55 Effect of alcohols on protein hydration 1zmy cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme 1zv5 Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme 1zvh Crystal stucture of the VHH domain D2-L24 in complex with hen egg white lysozyme 1zvy Crystal structure of the VHH D3-L11 in complex with hen egg white lysozyme 207l MUTANT HUMAN LYSOZYME C77A 208l MUTANT HUMAN LYSOZYME C77A 2a6u pH evolution of tetragonal HEWL at 4 degrees Celcius. 2a7d On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength 2a7f On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength 2aub Lysozyme structure derived from thin-film-based crystals 2b5z Hen lysozyme chemically glycosylated 2blx HEWL before a high dose x-ray ""burn"" 2bly HEWL after a high dose x-ray ""burn"" 2bpu The Kedge Holmium Derivative of Hen Egg-White Lysozyme at high resolution from Single Wavelength Anomalous Diffraction 2bqa CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqb CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqc CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqd CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqe CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqf CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqg CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqh CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqi CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqj CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqk CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bql CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqm CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqn CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2bqo CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2c8o lysozyme (1sec) and UV lasr excited fluorescence 2c8p lysozyme (60sec) and UV laser excited fluorescence 2cds LYSOZYME 2cgi Siras structure of tetragonal lysosyme using derivative data collected at the high energy remote Holmium Kedge 2cwi X-ray crystal structure analysis of recombinant wild-type canine milk lysozyme (apo-type) 2d4i Monoclinic hen egg-white lysozyme crystallized at pH4.5 form heavy water solution 2d4j Transformed monoclinic crystal of hen egg-white lysozyme from a heavy water solution 2d4k Monoclinic hen egg-white lysozyme crystallized at 313K 2d6b Novel Bromate Species trapped within a Protein Crystal 2d91 Structure of HYPER-VIL-lysozyme 2dqc Crystal structure of hyhel-10 FV mutant(Hy33f) complexed with hen egg lysozyme 2dqd Crystal structure of hyhel-10 FV mutant (Hy50f) complexed with hen egg lysozyme 2dqe Crystal structure of hyhel-10 FV mutant (Hy53a) complexed with hen egg lysozyme 2dqf Crystal structure of hyhel-10 FV mutant (y33ay53a) complexed with hen egg lysozyme 2dqg Crystal structure of hyhel-10 FV mutant (Hy53f) complexed with hen egg lysozyme 2dqh Crystal structure of hyhel-10 FV mutant (Hy58a) complexed with hen egg lysozyme 2dqi Crystal structure of hyhel-10 FV mutant (Ly50a) complexed with hen egg lysozyme 2dqj Crystal structure of hyhel-10 FV (wild-type) complexed with hen egg lysozyme at 1.8A resolution 2eiz Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex 2eks Crystal structure of humanized HyHEL-10 FV-HEN lysozyme complex 2epe Crystal structure analysis of Hen egg white lysozyme grown by capillary method 2eql CRYSTALLOGRAPHIC STUDIES OF A CALCIUM BINDING LYSOZYME FROM EQUINE MILK AT 2.5 ANGSTROMS RESOLUTION 2f2n Triclinic hen egg lysozyme cross-linked by glutaraldehyde 2f30 Triclinic cross-linked Lysozyme soaked with 4.5M urea 2f4a Triclinic cross-linked lysozyme soaked with thiourea 1.5M 2f4g Triclinic cross-linked lysozyme soaked in bromoethanol 1M 2fbb Crystal Structure Analysis of Hexagonal Lysozyme 2fbd The crystallographic structure of the digestive lysozyme 1 from Musca domestica at 1.90 Ang. 2fyc Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase-I in complex with alpha-lactalbumin, Ca and UDP-galactose 2fyd catalytic domain of bovine beta 1, 4-galactosyltransferase in complex with alpha-lactalbumin, glucose, Mn, and UDP-N-acetylgalactosamine 2g4n Anomalous substructure of alpha-lactalbumin 2g4p Anomalous substructure of lysozyme at pH 4.5 2g4q Anomalous substructure of lysozyme at pH 8.0 2gv0 The structure of the orthorhombic form of soft-shelled turtle lysozyme at 1.9 angstroms resolution 2h5z Crystallographic structure of digestive lysozyme 1 from Musca domestica bound to chitotetraose at 1.92 A resolution 2h9j Structure of Hen egg white lysozyme soaked with Ni2-Xylylbicyclam 2h9k Structure of Hen egg white lysozyme soaked with Ni-cyclam 2hea CONTRIBUTION OF WATER MOLECULES IN THE INTERIOR OF A PROTEIN TO THE CONFORMATIONAL STABILITY 2heb CONTRIBUTION OF WATER MOLECULES IN THE INTERIOR OF A PROTEIN TO THE CONFORMATIONAL STABILITY 2hec CONTRIBUTION OF WATER MOLECULES IN THE INTERIOR OF A PROTEIN TO THE CONFORMATIONAL STABILITY 2hed CONTRIBUTION OF WATER MOLECULES IN THE INTERIOR OF A PROTEIN TO THE CONFORMATIONAL STABILITY 2hee CONTRIBUTION OF WATER MOLECULES IN THE INTERIOR OF A PROTEIN TO THE CONFORMATIONAL STABILITY 2hef CONTRIBUTION OF WATER MOLECULES IN THE INTERIOR OF A PROTEIN TO THE CONFORMATIONAL STABILITY 2hs7 Multipattern rietveld refinement with protein powder data: An approach to higher resolution 2hs9 Multipattern Rietveld refinement with protein powder data: An approach to higher resolution 2hso Multipattern rietveld refinement with protein powder data: An approach to higher resolution 2htx Crystal Structure Analysis of Hen Egg White Lysozyme Crosslinked by Polymerized Glutaraldehyde in Acidic Environment 2hu1 Crystal structure Analysis of Hen Egg White Lyszoyme 2hu3 Parent Structure of Hen Egg White Lysozyme grown in acidic pH 4.8. Refinement for comparison with crosslinked molecules of lysozyme 2hub Structure of Hen Egg-White Lysozyme Determined from crystals grown in pH 7.5 2i25 Crystal structure analysis of the nurse shark New antigen Receptor PBLA8 variable domain in complex with lysozyme 2i26 Crystal structure analysis of the nurse shark new antigen receptor ancestral variable domain in complex with lysozyme 2i6z X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme 2iff STRUCTURE OF AN ANTIBODY-LYSOZYME COMPLEX: EFFECT OF A CONSERVATIVE MUTATION 2ihl LYSOZYME (E.C.3.2.1.17) (JAPANESE QUAIL) 2lhm CRYSTAL STRUCTURES OF THE APO-AND HOLOMUTANT HUMAN LYSOZYMES WITH AN INTRODUCED CA2+ BINDING SITE 2lym CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME AT A HYDROSTATIC PRESSURE OF 1000 ATMOSPHERES 2lyo CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN 90% ACETONITRILE-WATER 2lyz REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME 2lz2 THE THREE DIMENSIONAL STRUCTURE OF TURKEY EGG WHITE LYSOZYME AT 2.2 ANGSTROMS RESOLUTION 2lzh THE STRUCTURES OF THE MONOCLINIC AND ORTHORHOMBIC FORMS OF HEN EGG-WHITE LYSOZYME AT 6 ANGSTROMS RESOLUTION. 2lzt REFINEMENT OF TRICLINIC LYSOZYME. II. THE METHOD OF STEREOCHEMICALLY RESTRAINED LEAST-SQUARES 2mea CHANGES IN CONFORMATIONAL STABILITY OF A SERIES OF MUTANT HUMAN LYSOZYMES AT CONSTANT POSITIONS 2meb CHANGES IN CONFORMATIONAL STABILITY OF A SERIES OF MUTANT HUMAN LYSOZYMES AT CONSTANT POSITIONS 2mec CHANGES IN CONFORMATIONAL STABILITY OF A SERIES OF MUTANT HUMAN LYSOZYMES AT CONSTANT POSITIONS 2med CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2mee CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2mef CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2meg CHANGES IN CONFORMATIONAL STABILITY OF A SERIES OF MUTANT HUMAN LYSOZYMES AT CONSTANT POSITIONS. 2meh CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2mei CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 2nwd Structure of chemically synthesized human lysozyme at 1 Angstrom resolution 2pc2 Lysozyme Cocrystallized with Tris-dipicolinate Eu complex 2q0m Tricarbonylmanganese(I)-lysozyme complex : a structurally characterized organometallic protein 2rsc Solution Structure of the bombyx mori lysozyme 2vb1 HEWL at 0.65 angstrom resolution 2w1l THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 0.979 a wavelength 991 images data 2w1m THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 2.070 A WAVELENGTH with 2theta 30 degrees data 2w1x THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 1.284 360 images data 2w1y THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 1.540 A wavelength 180 images data 2war Hen Egg White Lysozyme E35Q chitopentaose complex 2x0a MPD-Lysozyme structure at 55.5 keV using a TRIXXEL CsI-aSi based digital imager and the new ESRF U22 undulator source at ID15 2xbr Raman crystallography of Hen White Egg Lysozyme - Low X-ray dose (0.2 MGy) 2xbs Raman crystallography of Hen White Egg Lysozyme - High X-ray dose (16 MGy) 2xjw Lysozyme-CO releasing molecule adduct 2xth K2PtBr6 binding to lysozyme 2ybh Nitrate X-ray induced reduction on HEWL crystals (2.31 MGy). 2ybi Nitrate X-ray induced reduction on HEWL crystals (6.62 MGy) 2ybj Nitrate X-ray induced reduction on HEWL crystals (12.31 MGy) 2ybl Nitrate X-ray induced reduction on HEWL crystals (17.9 MGy) 2ybm Nitrate X-ray induced reduction on HEWL crystals (23.3 MGy) 2ybn Nitrate X-ray induced reduction on HEWL crystals (28.6 MGy) 2ydg Ascorbate co-crystallized HEWL. 2yss Crystal structure of Humanized HYHEL-10 FV mutant(HQ39KW47Y)-HEN lysozyme complex 2yvb High resolution X-ray crystal structure of Tetragonal Hen egg white lysozyme 2z12 Structure of the transformed monoclinic lysozyme by controlled dehydration 2z18 Phase transition of monoclinic lysozyme crystal soaked in a 10% NaCl solution 2z19 Phase transition of monoclinic lysozyme crystal soaked in a saturated NaCl solution 2z2e Crystal Structure of Canine Milk Lysozyme Stabilized against Non-enzymatic Deamidation 2z2f X-ray Crystal Structure of Bovine Stomach Lysozyme 2zij Crystal Structure of Human Lysozyme Expressed in E. coli. 2zik Crystal Structure of Human Lysozyme from Pichia pastoris 2zil Crystal Structure of Human Lysozyme from Urine 2znw Crystal Structure of ScFv10 in Complex with Hen Egg Lysozyme 2znx 5-Fluorotryptophan Incorporated ScFv10 Complexed to Hen Egg Lysozyme 2zq3 The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.6 angstroms resolution 2zq4 The crystal structure of the orthorhombic form of hen egg white lysozyme at 2.0 angstroms resolution 2zwb Neutron crystal structure of wild type human lysozyme in D2O 2zyp X-ray structure of hen egg-white lysozyme with poly(allyl amine) 3a34 Effect of Ariginine on lysozyme 3a3q Structure of N59D HEN EGG-WHITE LYSOZYME in complex with (GlcNAc)3 3a3r Structure of N59D HEN EGG-WHITE LYSOZYME 3a67 Crystal Structure of HyHEL-10 Fv mutant LN31D complexed with hen egg white lysozyme 3a6b Crystal Structure of HyHEL-10 Fv mutant LN32D complexed with hen egg white lysozyme 3a6c Crystal Structure of HyHEL-10 Fv mutant LN92D complexed with hen egg white lysozyme 3a8z Crystal structure of hen egg white lysozyme 3a90 Crystal structure of hen egg white lysozyme soaked with 1mM RhCl3 3a91 Crystal structure of hen egg white lysozyme soaked with 5mM RhCl3 3a92 Crystal structure of hen egg white lysozyme soaked with 10mM RhCl3 3a93 Crystal structure of hen egg white lysozyme soaked with 30mM RhCl3 3a94 Crystal structure of hen egg white lysozyme soaked with 100mM RhCl3 3a95 Crystal structure of hen egg white lysozyme soaked with 100mM RhCl3 at pH3.8 3a96 Crystal structure of hen egg white lysozyme soaked with 100mM RhCl3 at pH2.2 3agg X-ray analysis of lysozyme in the absence of Arg 3agh X-ray analysis of lysozyme in the presence of 200 mM Arg 3agi High resolution X-ray analysis of Arg-lysozyme complex in the presence of 500 mM Arg 3ajn Structural basis of glycine amide on suppression of protein aggregation by high resolution X-ray analysis 3atn Glycine ethyl ester shielding on the aromatic surfaces of lysozyme: Implication for suppression of protein aggregation 3ato Glycine ethyl ester shielding on the aromatic surfaces of lysozyme: Implication for suppression of protein aggregation 3aw6 Crystal structure of tetragonal hen egg white lysozyme at 84.2% relative humidity 3aw7 Crystal structure of tetragonal hen egg white lysozyme at 71.9% relative humidity 3az4 Crystal structure of Co/O-HEWL 3az5 Crystal structure of Pt/O-HEWL 3az6 Crystal structure of Co/T-HEWL 3az7 Crystal structure of Pt/T-HEWL 3b0i Crystal structure of recombinant human alpha lactalbumin 3b0k Crystal structure of alpha-lactalbumin 3b0o Crystal structure of alpha-lactalbumin 3b6l Crystal structure of lysozyme folded in SDS and 2-methyl-2,4-pentanediol 3b72 Crystal structure of lysozyme folded in SDS and 2-methyl-2,4-pentanediol 3cb7 The crystallographic structure of the digestive lysozyme 2 from Musca domestica at 1.9 Ang. 3d9a High Resolution Crystal Structure Structure of HyHel10 Fab Complexed to Hen Egg Lysozyme 3e3d Structure of hen egg white lysozyme with the magic triangle I3C 3eba CAbHul6 FGLW mutant (humanized) in complex with human lysozyme 3ems Effect of Ariginine on lysozyme 3exd Sulfur-SAD phased HEWL Crystal 3f6z Crystal structure of Pseudomonas aeruginosa MliC in complex with hen egg white lysozyme 3fe0 X-ray crystal structure of wild type human lysozyme in D2O 3g3a Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen 3g3b Structure of a lamprey variable lymphocyte receptor mutant in complex with a protein antigen 3hfm STRUCTURE OF AN ANTIBODY-ANTIGEN COMPLEX. CRYSTAL STRUCTURE OF THE HY/HEL-10 FAB-LYSOZYME COMPLEX 3iju Chicken egg white lysozyme by highly ordered APA (Anodic Porous Alumina) nanotemplate crystallization method 3ijv Chicken egg white lysozyme by classical hanging drop vapour diffusion method 3j4g Structure of lysozyme solved by MicroED to 2.9 A 3j6k 3J6K 3kam Hen Egg White Lysozyme Derivatized with rhenium(I) diaquatricarbonyl cation 3lhm CRYSTAL STRUCTURES OF THE APO-AND HOLOMUTANT HUMAN LYSOZYMES WITH AN INTRODUCED CA2+ BINDING SITE 3ln2 Crystal Structure of a Charge Engineered Human Lysozyme Variant 3lym CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME AT A HYDROSTATIC PRESSURE OF 1000 ATMOSPHERES 3lyo CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN 95% ACETONITRILE-WATER 3lyt COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES 3lyz REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME 3lz2 STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION 3lzt REFINEMENT OF TRICLINIC LYSOZYME AT ATOMIC RESOLUTION 3m18 Crystal structure of variable lymphocyte receptor VLRA.R2.1 in complex with hen egg lysozyme 3m3u Effect of temperature on tryptophan fluorescence in lysozyme crystals 3n9a Mite-y Lysozyme: Vegemite 3n9c Mite-y Lysozyme: Marmite 3n9e Mite-y Lysozyme: Promite 3ojp D52N Mutant of Hen Egg White Lysozyme (HEWL) 3ok0 E35A Mutant of Hen Egg White Lysozyme (HEWL) 3otp Crystal structure of the DegP dodecamer with a model substrate 3p4z Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme 3p64 Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme 3p65 Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme 3p66 Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme 3p68 Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme 3qe8 Crystal Structure Analysis of Lysozyme-bound fac-[Re(CO)3(H2O)(Im)]+ 3qng Crystal Structure Analysis of Lysozyme-bound fac-[Re(CO)3(L-serine)] 3qy4 Crystallization and in situ data collection of Lysozyme using the Crystal Former 3rnx Crystal Structure of Lysozyme in 30% ethanol 3rt5 Lysozyme in 30% propanol 3ru5 Silver Metallated Hen Egg White Lysozyme at 1.35 A 3rw8 Crystal structure of lysozyme in 40% ethanol 3rz4 Hen egg-white lysozyme in HEPES buffer at pH 7.5 3sp3 Lysozyme in 20% sucrose 3t6u Crystal Structure of Lysozyme in 40% sucrose 3tmu X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Undosed) 3tmv X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Dose=0.12MGy) 3tmw X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Undosed) 3tmx X-Ray Radiation Damage to HEWL Crystals soaked in 100mM Sodium Nitrate (Dose=1.9MGy) 3txb HEWL co-crystallization with cisplatin in aqueous media with glycerol as the cryoprotectant 3txd HEWL co-crystallization with carboplatin in aqueous media with glycerol as the cryoprotectant 3txe HEWL co-crystallization with carboplatin in aqueous media with paratone as the cryoprotectant 3txf HEWL co-crystallization with cisplatin in DMSO media with glycerol as the cryoprotectant 3txg HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant 3txh HEWL co-crystallization with carboplatin in DMSO media with glycerol as the cryoprotectant 3txi HEWL co-crystallization with carboplatin in DMSO media with paratone as the cryoprotectant 3txj HEWL co-crystallization with NAG with silicone oil as the cryoprotectant 3txk HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant at pH 6.5 3ulr Lysozyme contamination facilitates crystallization of a hetero-trimericCortactin:Arg:Lysozyme complex 3w6a Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked wiht 5mM [Ru(benzene)Cl2]2 3wl2 3WL2 3wmk 3WMK 3wpj 3WPJ 3wpk 3WPK 3wpl 3WPL 3wu7 3WU7 3wu8 3WU8 3wu9 3WU9 3wua 3WUA 3wul 3WUL 3wum 3WUM 3wun 3WUN 3wvx 3WVX 3wvy 3WVY 3ww5 3WW5 3ww6 3WW6 3wxt 3WXT 3wxu 3WXU 3zek Hen egg-white lysozyme structure determined at room temperature by in- situ diffraction in ChipX 3zvq Crystal Structure of proteolyzed lysozyme 4a7d X-ray crystal structure of HEWL flash-cooled at high pressure 4a8a Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme 4a8b Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes 4aga Hofmeister effects of ionic liquids in protein crystallization: direct and water-mediated interactions 4axt CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME FROM A AUTO HARVESTED CRYSTAL, Control Experiment 4b0d CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME FROM AN AUTO HARVESTED CRYSTAL 4b1a Crystal structure of lysozyme with Keggin molecule 4b49 1.15 A Structure of Lysozyme Crystallized without 2-methyl-2,4- pentanediol 4b4e 1.00 A Structure of Lysozyme Crystallized with (R)-2-methyl-2,4- pentanediol 4b4i 1.20 A Structure of Lysozyme Crystallized with (S)-2-methyl-2,4- pentanediol 4b4j 1.25 A Structure of Lysozyme Crystallized with (RS)-2-methyl-2,4- pentanediol 4bad Hen egg-white lysozyme structure in complex with the europium tris- hydroxymethyltriazoledipicolinate complex at 1.35 A resolution. 4baf Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution. 4bap Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethylcholinetriazoledipicolinate complex at 1.21 A resolution. 4bs7 Hen egg-white lysozyme structure determined at room temperature by in- situ diffraction and SAD phasing in ChipX 4c3w 4C3W 4cj2 Crystal structure of HEWL in complex with affitin H4 4d9z Lysozyme at 318K 4dc4 Lysozyme Trimer 4dd0 EVAL processed HEWL, cisplatin aqueous glycerol 4dd1 EVAL processed HEWL, cisplatin aqueous paratone 4dd2 EVAL processed HEWL, carboplatin aqueous glycerol 4dd3 EVAL processed HEWL, carboplatin aqueous paratone 4dd7 EVAL processed HEWL, carboplatin DMSO glycerol 4dd9 EVAL processed HEWL, carboplatin DMSO paratone 4dda EVAL processed HEWL, NAG 4ddb EVAL processed HEWL, cisplatin DMSO paratone pH 6.5 4ddc EVAL processed HEWL, cisplatin DMSO NAG silicone oil 4dt3 Crystal structure of zinc-charged lysozyme 4e3u Crystal Structure of Hen Egg White Lysozyme Cryoprotected in Proline 4eof Lysozyme in the presence of arginine 4et8 Hen egg-white lysozyme solved from 40 fs free-electron laser pulse data 4et9 Hen egg-white lysozyme solved from 5 fs free-electron laser pulse data 4eta Lysozyme, room temperature, 400 kGy dose 4etb lysozyme, room temperature, 200 kGy dose 4etc Lysozyme, room temperature, 24 kGy dose 4etd Lysozyme, room-temperature, rotating anode, 0.0026 MGy 4ete Lysozyme, room-temperature, rotating anode, 0.0021 MGy 4fjr Mode of interaction of Merocyanine 540 with HEW Lysozyme 4g49 Room temperature X-ray diffraction of cisplatin binding to HEWL in aqueous media after 15 months of crystal storage 4g4b Room temperature X-ray diffraction study of cisplatin binding to HEWL in DMSO media with NAG after 7 months of crystal storage 4g4c Room temperature X-ray diffraction study of carboplatin binding to HEWL in DMSO media after 13 months of crystal storage 4g4h 100K X-ray diffraction study of carboplatin binding to HEWL in DMSO media after 13 months of crystal storage 4gcb 100K X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL 4gcc Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 1 4gcd Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 2 4gce Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3 4gcf Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 4 4gla OBody NL8 bound to hen egg-white lysozyme 4glv OBody AM3L09 bound to hen egg-white lysozyme 4gn3 OBody AM1L10 bound to hen egg-white lysozyme 4gn4 OBody AM2EP06 bound to hen egg-white lysozyme 4gn5 OBody AM3L15 bound to hen egg-white lysozyme 4h1p Use of Europium for SAD Phasing at the Cu K alpha wavelength 4h8x Radiation damage study of lysozyme - 0.07 MGy 4h8y Radiation damage study of lysozyme- 0.14 MGy 4h8z Radiation damage study of lysozyme - 0.21 MGy 4h90 Radiation damage study of lysozyme - 0.28 MGy 4h91 Radiation damage study of lysozyme - 0.35 MGy 4h92 Radiation damage study of lysozyme- 0.42 MGy 4h93 Radiation damage study of lysozyme - 0.49 MGy 4h94 Radiation damage in lysozyme - 0.56 MGy 4h9a Radiation damage study of lysozyme - 0.63 MGy 4h9b Radiation damage study of lysozyme - 0.70 MGy 4h9c Radiation damage study of lysozyme - 0.77 MGy 4h9e Radiation damage study of lysozyme - 0.84 MGy 4h9f Radiation damage study of lysozyme - 0.91 MGy 4h9h Radiation damage study of lysozyme - 0.98 MGy 4h9i Radiation damage study of lysozyme - 1.05 MGy 4hp0 Crystal Structure of Hen Egg White Lysozyme in complex with GN3-M 4hpi Crystal Structure of Hen Egg White Lysozyme complex with GN2-M 4hsf Lysozyme with Arginine at 318K 4htk Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 2.17 x 10e+12 X-ray photons 4htn Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 1.32 x 10e+12 X-ray photons 4htq Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 6.70 x 10e+11 X-ray photons 4hv1 Laser-induced microfragmentation of lysozyme crystals allows X-ray nanodiffraction characterization of individual domains (lb4) 4hv2 Laser-induced microfragmentation of lysozyme crystals allows X-ray nanodiffraction characterization of individual domains (lb5) 4i0c The structure of the camelid antibody cAbHuL5 in complex with human lysozyme 4i8s Hen Lysozyme protein crystallization via standard hanging drop vapor diffusion 4ias HEW Lysozyme by langmuir- blodgett modified vapour diffusion 4iat HEW Lysozyme by langmuir- blodgett modified vapour diffusion 4ii8 Lysozyme with Benzyl alcohol 4j1a X-ray structure of the adduct between hen egg white lysozyme and AziRu (green crystal) 4j1b X-ray structure of the adduct between hen egg white lysozyme and AziRu (black crystal) 4j7v Crystal structure of cross-linked hen egg white lysozyme soaked with 5mM [Ru(benzene)Cl2]2 4kxi 4KXI 4l41 Human Lactose synthase: A 2:1 complex between human alpha-lactalbumin and human beta1,4-galactosyltransferase 4lfp X-ray structure of the adduct between hen egg white lysozyme and a homoleptic gold(I) complex with the saccharynate ligand 4lfx X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers 4lgk X-ray structure of the adduct between hen egg white lysozyme and Au2Phen, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers 4lt0 4LT0 4lt1 4LT1 4lt2 4LT2 4lt3 4LT3 4lyb 4LYB 4lyc 4LYC 4lym CRYSTAL STRUCTURE OF LOW HUMIDITY TETRAGONAL LYSOZYME AT 2.1-ANGSTROMS RESOLUTION. VARIABILITY IN HYDRATION SHELL AND ITS STRUCTURAL CONSEQUENCES 4lyo CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN NEAT ACETONITRILE, THEN BACK-SOAKED IN WATER 4lyt COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES 4lyz REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME 4lzt ATOMIC RESOLUTION REFINEMENT OF TRICLINIC HEW LYSOZYME AT 295K 4m4o Crystal structure of the aptamer minE-lysozyme complex 4m6d Crystal structure of the aptamer minF-lysozyme complex. 4ml7 4ML7 4mr1 4MR1 4n0j 4N0J 4n1c 4N1C 4n1e 4N1E 4n5r Hen egg-white lysozyme phased using free-electron laser data 4n8z In situ lysozyme crystallized on a MiTeGen micromesh with benzamidine ligand 4n9r 4N9R 4neb 4NEB 4nfv 4NFV 4ng1 4NG1 4ng8 4NG8 4ngi 4NGI 4ngj 4NGJ 4ngk 4NGK 4ngl 4NGL 4ngo 4NGO 4ngv 4NGV 4ngw 4NGW 4ngy 4NGY 4ngz 4NGZ 4nhi 4NHI 4nhp 4NHP 4nhq 4NHQ 4nhs 4NHS 4nht 4NHT 4nij 4NIJ 4nsg 4NSG 4nsh 4NSH 4nsi 4NSI 4nsj 4NSJ 4nwe 4NWE 4nwh 4NWH 4ny5 X-ray structure of the adduct formed between hen egg white lysozyme and NAMI-A 4o34 4O34 4ooo 4OOO 4oot 4OOT 4owa 4OWA 4owb 4OWB 4owc 4OWC 4owe 4OWE 4owh 4OWH 4p2e Acoustic transfer of protein crystals from agar pedestals to micromeshes for high throughput screening of heavy atom derivatives 4pgj 4PGJ 4phi 4PHI 4ppo 4PPO 4prq 4PRQ 4pru 4PRU 4qeq 4QEQ 4qgz 4QGZ 4qy9 4QY9 4r0f 4R0F 4r6c 4R6C 4rds 4RDS 4rlm 4RLM 4rln 4RLN 4rw1 4RW1 4rw2 4RW2 4tsa 4TSA 4tsb 4TSB 4tsc 4TSC 4ttd 4TTD 4tun 4TUN 4tws 4TWS 4u3x 4U3X 4uwn 4UWN 4uwu 4UWU 4uwv 4UWV 4w94 4W94 4w96 4W96 4wg1 4WG1 4wg7 4WG7 4wl6 4WL6 4wl7 4WL7 4wld 4WLD 4wlt 4WLT 4wlx 4WLX 4wly 4WLY 4wm1 4WM1 4wm2 4WM2 4wm3 4WM3 4wm4 4WM4 4wm5 4WM5 4wm6 4WM6 4wmg 4WMG 4wo6 4WO6 4wo9 4WO9 4woa 4WOA 4x3b 4X3B 4xad 4XAD 4xen 4XEN 4xjb 4XJB 4xjd 4XJD 4xjf 4XJF 4xjg 4XJG 4xjh 4XJH 4xji 4XJI 4xn6 4XN6 4xyy 4XYY 4yem 4YEM 4yen 4YEN 4yeo 4YEO 4yf2 4YF2 4ym8 4YM8 4yop 4YOP 4z3m 4Z3M 4z41 4Z41 4z46 4Z46 4z98 4Z98 4zee 4ZEE 4zfp 4ZFP 4zix 4ZIX 5a3e 5A3E 5a3z 5A3Z 5amy 5AMY 5apc 5APC 5apd 5APD 5ape 5APE 5apf 5APF 5b05 5B05 5b06 5B06 5b07 5B07 5b59 5B59 5c6i 5C6I 5c6j 5C6J 5c6l 5C6L 5d5c 5D5C 5d5f 5D5F 5dl9 5DL9 5dla 5DLA 5dm9 5DM9 5e4p 5E4P 5e9r 5E9R 5ebh 5EBH 5f14 5F14 5f16 5F16 5f81 5F81 5f9u 5F9U 5f9x 5F9X 5fcp 5FCP 5fdj 5FDJ 5fek 5FEK 5fel 5FEL 5fst 5FST 5hll 5HLL 5hmj 5HMJ 5hmv 5HMV 5hnc 5HNC 5hnl 5HNL 5hq1 5HQ1 5i5q 5I5Q 5idd 5IDD 5j7c 5J7C 5jen 5JEN 5kj9 5KJ9 5kxk 5KXK 5kxl 5KXL 5kxm 5KXM 5kxn 5KXN 5kxo 5KXO 5kxp 5KXP 5kxr 5KXR 5kxs 5KXS 5kxt 5KXT 5kxw 5KXW 5kxx 5KXX 5kxy 5KXY 5kxz 5KXZ 5ky1 5KY1 5l3h 5L3H 5l3i 5L3I 5l9j 5L9J 5lin 5LIN 5lio 5LIO 5lvg 5LVG 5lvh 5LVH 5lvi 5LVI 5lvj 5LVJ 5lvk 5LVK 5lxw 5LXW 5lym STUDIES OF MONOCLINIC HEN EGG WHITE LYSOZYME. IV. X-RAY REFINEMENT AT 1.8 ANGSTROM RESOLUTION AND A COMPARISON OF THE VARIABLE REGIONS IN THE POLYMORPHIC FORMS 5lyt COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES 5lyz REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME 5m1y 5M1Y 5t3f 5T3F 6lyt COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES 6lyz REAL-SPACE REFINEMENT OF THE STRUCTURE OF HEN EGG-WHITE LYSOZYME 7lyz PROTEIN MODEL BUILDING BY THE USE OF A CONSTRAINED-RESTRAINED LEAST-SQUARES PROCEDURE 8lyz AN X-RAY STUDY OF THE STRUCTURE AND BINDING PROPERTIES OF IODINE-INACTIVATED LYSOZYME 9lyz X-RAY CRYSTALLOGRAPHY OF THE BINDING OF THE BACTERIAL CELL WALL TRISACCHARIDE NAM-NAG-NAM TO LYSOZYME - Links (links to other resources describing this domain)
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PROSITE PS00128 INTERPRO IPR001916