Leukotriene A4 hydrolase, C-terminal
SMART accession number:SM01263
Description: Members of this family adopt a structure consisting of two layers of parallel alpha-helices, five in the inner layer and four in the outer, arranged in an antiparallel manner, with perpendicular loops containing short helical segments on top. They are required for the formation of a deep cleft harbouring the catalytic Zn2+ site in Leukotriene A4 hydrolase (PUBMED:11175901).
Family alignment:
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There are 1080 Leuk-A4-hydro_C domains in 1080 proteins in SMART's nrdb database.

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