PKS_MT

Methyltransferase in polyketide synthase (PKS) enzymes.

• SMART accession number: SM00828
• Description: -
• Interpro abstract (IPR020803):

  Methyl transfer from the ubiquitous donor S-adenosyl-L-methionine (SAM) to either nitrogen, oxygen or carbon atoms is frequently employed in diverse organisms ranging from bacteria to plants and mammals. The reaction is catalyzed by methyltransferases (Mtases) and modifies DNA, RNA, proteins and small molecules, such as catechol for regulatory purposes. The various aspects of the role of DNA methylation in prokaryotic restriction-modification systems and in a number of cellular processes in eukaryotes including gene regulation and differentiation is well documented.

  This entry represents a methyltransferase domain found in polyketide synthases.

There are 108 PKS_MT domains in 106 proteins in SMART's nrdb database.

Cellular role (predicted cellular role)

Cellular role: metabolism

Links (links to other resources describing this domain)

• INTERPRO: IPR020803