AI-2E_transport

• PFAM accession number: PF01594
• Interpro abstract (IPR002549):

  This entry consists of proteins from eukaryotes and prokarytotes. It includes Escherichia coli autoinducer-2 (AI-2) transport protein TqsA (YdgG), which controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [ (PUBMED:16385049) ]. TqsA exhibit a uniform topology with 8 putative transmembrane segments (TMSs), a structure shared by proteins in this family. The function of proteins in this family are mostly unknown, however, it has been suggested that they may transport a variety of compounds, possibly all related in structure [ (PUBMED:20559013) ]. This entry also includes transport proteins such as sodium-lithium/proton antiporter from Halobacillus [ (PUBMED:28374790) ] and sporulation protein YtvI from Bacillus subtilis, a putative permease [ (PUBMED:12662922) ].

  This entry also includes uncharacterised transmembrane protein 245 (TMEM245) from eukaryotes.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry AI-2E_transport