The domain within your query sequence starts at position 4 and ends at position 55; the E-value for the APC_N_CC domain shown below is 6e-32.
ASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSI
APC_N_CC |
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PFAM accession number: | PF16689 |
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Interpro abstract (IPR032038): | This entry represents the N-terminal, coiled-coil dimerisation domain of the adenomatosis polyposis coli (APC) tumour-repressor proteins. It plays a key role in the regulation of cellular levels of the oncogene product beta-catenin. Coiled-coil regions are binding repeats that in this case bind to the armadillo repeat region of beta-catenin [ (PUBMED:10926498) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry APC_N_CC