The domain within your query sequence starts at position 1 and ends at position 477; the E-value for the ARHGEF5_35 domain shown below is 3.1e-220.

MEAEEPEYGVSTEVPDIEELKTIPEGIMRSSQIPALDPEAQEDRDPSYKWTDGHRPVMNQ
SKVLRDMGDHTPNSMAIFFKKESSDMETSQEILLAEACNTPDQQEAVIQSLKDRLSRTIA
APELLACAVQEEWLDIPSKLDNRVGAELQSELMSLTLAVSKEKEEEETSPDTSIPRGSWP
PCKTHPGETEQTQGSGSELLRQGKQLQLEATQENQGQEGFLQSQEAQGLEEQEGQEVEIQ
EEGTLNEGICFGGLLGEQEEVEEGFNGNEEEQKQGQIQSYMLLGGQWENEGLSGELEGLN
YSERGQENRERRVWVLRDSEEEGQDQESREVEERRVATQYTENQRLVEKSEIVKRKQRDH
DQTGKVMPVRDQKEVVDSGDRVQGNGDSGGQTAVEGSRPGEDSKPSLPVASVDPEVLSPG
TLFPGISSSVADIPQIQKEPVCEELSPQAPALEPTEWSHQPISPPASFAPEESLDNR

ARHGEF5_35

• PFAM accession number: PF15441
• Interpro abstract (IPR029212):

  This entry represents the N-terminal domain of Rho guanine nucleotide exchange factor 5 (also known as Ephexin3 or TIM) and Rho guanine nucleotide exchange factor 5-like (also known as Rho guanine nucleotide exchange factor 35).

This is a PFAM domain. For full annotation and more information, please see the PFAM entry ARHGEF5_35