ApbA_C

• PFAM accession number: PF08546
• Interpro abstract (IPR013752):

  This is the C-terminal domain of 2-dehydropantoate 2-reductases also known as ketopantoate reductases [ (PUBMED:11724562) ]. The reaction catalysed by this enzyme is: (R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH. It is required for the synthesis of thiamine via the the alternative pyrimidine biosynthetic (APB) pathway [ (PUBMED:9721324) (PUBMED:9488683) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry ApbA_C