The domain within your query sequence starts at position 795 and ends at position 1509; the E-value for the CEP170_C domain shown below is 8e-260.
IQNESKRRKAEEIPKCQASKGDKKESSKSLVRQGSFTIDKPSSNIPIELIPHINKQNSSV PTALALTSASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPS YNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDVTKSGSR EKIEKKAKSRSADIGARADGRKFVQSSGRIRQPSIDLTDDDQTSSVPHSAISDIMSSDQE TYSCKSHGRTPLTSADEHNIHSKLEGGKATKSKTSPVASGSTSKSTTLPRPRPTRTSLLR RARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRTISRIDLLAQPRRTRLGSLSAR SDSEATISRSSASARTAEAVIRSGARLVPSDKLSPRTRANSISRLSDSKVKSMSSTHGSP SVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHR IKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTP GSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSVDSRPQPAEH PDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIE NKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFP
CEP170_C |
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PFAM accession number: | PF15308 |
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Interpro abstract (IPR029300): | This entry represents the C terminus of centrosomal protein of 170kDa (CEP170) [ (PUBMED:15616186) ]. Centrosomal protein of 170kDa (Cep170) plays a role in microtubule organisation [ (PUBMED:15616186) ]. Human Cep170 is constantly expressed throughout the cell cycle, but phosphorylated during mitosis. Cep170 is a substrate of Polo-like kinase 1 (Plk1) [ (PUBMED:15616186) ]. It is associated with the mature mother centriole. Cep170 is also required for Kif2b-induced microtubule depolymerisation [ (PUBMED:23087211) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry CEP170_C