The domain within your query sequence starts at position 2 and ends at position 223; the E-value for the CHGN domain shown below is 5.8e-45.
EYRHVTLFRPFGPLMKVKNELIDITRSVINIIVPLAERTEAFSQFMQNFRDVCIHQDKRI HLTVVYFGKEGLSKVKSILESVSSESDFHNYTLVSLDEEFNRGRGLNVGARAWDKGEVLM FFCDVDIYFSAEFLNSCRLNAEPGKKVFYPVVFSLYNPAIVYANQDVPPPVEQQLVHKKD SGFWRDFGFGMTCQYQSDFLSVGGFDMEVKGWGGEDVHLYRK
CHGN |
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PFAM accession number: | PF05679 |
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Interpro abstract (IPR008428): | This family represents Chondroitin N-acetylgalactosaminyltransferase. Proteins have a type II transmembrane topology. The enzyme is involved in the biosynthetic initiation and elongation of chondroitin sulphate and is the key enzyme responsible for the selective chain assembly of chondroitin/dermatan sulphate on the linkage region tetrasaccharide common to various proteoglycans containing chondroitin/dermatan sulphate or heparin/heparan sulphate chains [ (PUBMED:11788602) (PUBMED:11514575) ]. |
GO component: | Golgi cisterna membrane (GO:0032580) |
GO function: | acetylgalactosaminyltransferase activity (GO:0008376) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry CHGN