The domain within your query sequence starts at position 5 and ends at position 102; the E-value for the CH_2 domain shown below is 3.1e-25.



PFAM accession number:PF06294
Interpro abstract (IPR010441):

This entry represents a domain known as Spef, which is a region of sperm flagellar proteins. It probably exerts a role in spermatogenesis in that the protein is expressed predominantly in adult tissue. It is present in the tails of developing and epididymal sperm internal to the fibrous sheath and around the dense outer fibres of the sperm flagellum [ (PUBMED:15979255) ]. The amino-terminal domain (residues 1-110) shows a possible calponin homology (CH) domain; however Spef does not bind actin directly under in vitro conditions, so the function of the amino-terminal calponin-like domain is unclear [ (PUBMED:15979255) ]. Transcription aberrations leading to a truncated protein result in immotile sperm [ (PUBMED:16549801) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry CH_2