The domain within your query sequence starts at position 166 and ends at position 190; the E-value for the Calponin domain shown below is 6e-20.



PFAM accession number:PF00402
Interpro abstract (IPR000557): Calponin [(PUBMED:8130072), (PUBMED:8144658)] is a thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin MgATPase activity. Calponin is a basic protein of approximately 34 Kd. Multiple isoforms are found in smooth muscles. Calponin contains three repeats of a well conserved 26 amino acid domain. Such a domain is also found in vertebrate smooth muscle protein (SM22 or transgelin), and a number of other proteins whose physiological role is not yet established, including Drosophila synchronous flight muscle protein SM20, Caenorhabditis elegans unc-87 protein [(PUBMED:7929573)], rat neuronal protein NP25 [(PUBMED:8015377)], and an Onchocerca volvulus antigen [(PUBMED:7935620)].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Calponin