Capsid_NCLDV

• PFAM accession number: PF04451
• Interpro abstract (IPR007542):

  The entry includes major capsid proteins (vp54 and vp72) found in Iridoviruses, Phycodnaviruses, Asfarviruses and Ascoviruses, which are all type II dsDNA viruses with no RNA stage. This is the most abundant structural protein and can account for up to 45% of virion protein [ (PUBMED:10082389) ]. The structure of vp54 has been determined from Paramecium bursaria Chlorella virus 1 (PBCV-1), a very large icosahedral virus containing an internal membrane enclosed within a glycoprotein coat. The vp54 protein is a duplication consisting of two domains with a similar fold packed together like the nucleoplasmin subunits. The vp54 protein forms a trimer, where the domains are arranged around a pseudo 6-fold axis. The domains have a beta-sandwich structure consisting of 8 strands in two sheets with a jelly-roll topology [ (PUBMED:12411581) ].

• GO function: structural molecule activity (GO:0005198)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Capsid_NCLDV