The domain within your query sequence starts at position 25 and ends at position 141; the E-value for the CathepsinC_exc domain shown below is 1.5e-48.
DTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEATEEKVVVHLKKLDTAYDELGNSGHF TLIYNQGFEIVLNDYKWFAFFKYEVRGHTAISYCHETMTGWVHDVLGRNWACFVGKK
CathepsinC_exc |
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PFAM accession number: | PF08773 |
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Interpro abstract (IPR014882): | Cathepsin C (dipeptidyl peptidase I) is the physiological activator of a group of serine proteases. This protein corresponds to the exclusion domain whose structure excludes the approach of a polypeptide apart from its termini. It forms an enclosed beta barrel structure composed from 8 anti-parallel beta strands [ (PUBMED:11726493) ]. Based on a structural comparison and interaction data, it is suggested that the exclusion domain originates from a metallo-protease inhibitor [ (PUBMED:11726493) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry CathepsinC_exc