Cellsynth_D

• PFAM accession number: PF03500
• Interpro abstract (IPR022798):

  An operon encoding 4 proteins required for bacterial cellulose biosynthesis (bcs) in Acetobacter xylinus (Gluconacetobacter xylinus) has been isolated via genetic complementation with strains lacking cellulose synthase activity [ (PUBMED:2146681) ]. Nucleotide sequence analysis showed the cellulose synthase operon to consist of 4 genes, designated bcsA, bcsB, bcsC and bcsD, all of which are required for maximal bacterial cellulose synthesis in A. xylinum.

  The calculated molecular mass of the protein encoded by bcsD is 17.3kDa [ (PUBMED:2146681) ]. The function of BcsD is unknown.

  Cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues, is the major component of wood and thus paper, and is synthesized by plants, most algae, some bacteria and fungi, and even some animals. The genes that synthesize cellulose in higher plants differ greatly from the well-characterised genes found in Acetobacter and Agrobacterium spp. More correctly designated as "cellulose synthase catalytic subunits", plant cellulose synthase (CesA) proteins are integral membrane proteins, approximately 1,000 amino acids in length. There are a number of highly conserved residues, including several motifs shown to be necessary for processive glycosyltransferase activity [ (PUBMED:8901635) ].

  This entry represents the D subunit from bacterial cellulose synthase.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Cellsynth_D