Channel_Tsx

Channel_Tsx
PFAM accession number:PF03502
Interpro abstract (IPR018013):

The tsx gene of Escherichia coli encodes an outer membrane protein, Tsx, which constitutes the receptor for colicin K and Bacteriophage T6, and functions as a substrate-specific channel for nucleosides and deoxy-nucleosides [ (PUBMED:2265760) ]. The protein contains 294 amino acids, the first 22 of which are characteristic of a bacterial signal sequence peptide. The putative mature form of Tsx contains 272 residues with a calculated Mr of 31418. The Tsx sequence shows an even distribution of charged residues and lacks extensive hydrophobic stretches [ (PUBMED:2265760) ]. Tsx shows no significant similarities to the channel-forming proteins OmpC, OmpF, PhoE and LamB from the E. coli outer membrane.

This entry also contains related proteins of unknown function.

GO component:cell outer membrane (GO:0009279)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Channel_Tsx