SMART: Pfam domain Cpta

Cpta_toxin

PFAM accession number:	PF07254
Interpro abstract (IPR009883):	This family includes bacterial proteins including the probable inner membrane protein YgfX from Escherichia coli (formerly known as CptA). This had been thought to be a toxin, but it has no effect on cell growth [ (PUBMED:23657679) ]. It has been shown to interacts with the cytoskeletal proteins FtsZ and MreB and to inhibit FtsZ GTP-dependent and MreB ATP-dependent polymerization [ (PUBMED:22239607) ]. In Serratia strains deficient in sdhE-ygfX, YgfX restores production of the antibiotic prodigiosin [ (PUBMED:22474332) ].

PFAM accession number:

PF07254

Interpro abstract (IPR009883):

This family includes bacterial proteins including the probable inner membrane protein YgfX from Escherichia coli (formerly known as CptA). This had been thought to be a toxin, but it has no effect on cell growth [ (PUBMED:23657679) ]. It has been shown to interacts with the cytoskeletal proteins FtsZ and MreB and to inhibit FtsZ GTP-dependent and MreB ATP-dependent polymerization [ (PUBMED:22239607) ]. In Serratia strains deficient in sdhE-ygfX, YgfX restores production of the antibiotic prodigiosin [ (PUBMED:22474332) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Cpta_toxin