Cytochrom_C_asm

• PFAM accession number: PF01578
• Interpro abstract (IPR002541):

  This domain is found in various proteins involved in cytochrome c assembly from mitochondria, chloroplast and bacteria; including among others CycK from Rhizobium leguminosarum [ (PUBMED:7665469) ], CcmC and CcmF from Escherichia coli [ (PUBMED:7635817) ], CcsA from Chlamydomonas [ (PUBMED:8617725) ], and orf240 from Triticum aestivum (wheat) mitochondria [ (PUBMED:7529870) ].

  CcmC interacts directly with heme, and it is the only protein of the ccm operon that is strictly required for heme transfer [ (PUBMED:10339610) ]. CcmF contains a b-type heme and is thought to be a cytochrome c synthetase [ (PUBMED:22066495) ]. CcsA is required during biogenesis of c-type cytochromes at the step of heme attachment [ (PUBMED:8617725) ]. R. leguminosarum CycK and wheat orf240 also contain a putative heme-binding motif [ (PUBMED:7665469) (PUBMED:7529870) ].

• GO process: cytochrome complex assembly (GO:0017004)
• GO function: heme binding (GO:0020037)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Cytochrom_C_asm