The domain within your query sequence starts at position 40 and ends at position 196; the E-value for the DERM domain shown below is 1e-37.
NLNRQGFSYQCPHGQVVVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAG MEWYQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPSHYGEDMDM ISYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDC
DERM |
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PFAM accession number: | PF14704 |
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Interpro abstract (IPR026645): | This family includes dermatopontin, millepora cytotoxin-1 and hemagglutinin/amebocyte aggregation factor. Dermatopontin is a small molecular weight protein in the extracellular matrix, which has been reported to be involved in different functions [ (PUBMED:16987749) ]. It seems to mediate adhesion by cell surface integrin binding [ (PUBMED:19928997) ]. It interacts with transforming growth factor beta [ (PUBMED:9895299) ]. A role of this protein in cell proliferation [ (PUBMED:14980498) ] and collagen fibrillogenesis [ (PUBMED:12230512) ] has also been reported. Millepora cytotoxin-1 is a toxin from fire coral with hemagglutination activity on erythrocytes [ (PUBMED:17983598) ]. Hemagglutinin/amebocyte aggregation factor is able to induce both aggregation of amebocytes and agglutination of erythrocytes [ (PUBMED:1429596) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry DERM