DNA_III_psi

• PFAM accession number: PF03603
• Interpro abstract (IPR004615):

  DNA-directed DNA polymerase ( EC 2.7.7.7 ) catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The enzyme also has 3' to 5' exonuclease activity. It has a core composed of alpha, epsilon and theta chains, that associate with a tau subunit which allows the core dimerization to form the PolIII' complex. PolIII' associates with the gamma complex (gamma, delta, delta', psi and chi chains) and with the beta chain. This family is the psi subunit, the small subunit of the DNA polymerase III holoenzyme in Escherichia coli and related species, whose exact function is not known. It appears to have a narrow taxonomic distribution, being restricted to the gammaproteobacteria.

• GO process: DNA replication (GO:0006260)
• GO function: 3'-5' exonuclease activity (GO:0008408), DNA-directed DNA polymerase activity (GO:0003887)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DNA_III_psi