SMART: Pfam domain DUF1933

DUF1933

PFAM accession number:	PF09147
Interpro abstract (IPR015230):	This domain is found in the N-terminal of carbapenam-3-carboxylate synthase (carA), and is composed of two antiparallel six-stranded beta-sheets that form a sandwich, flanked on each side by two alpha-helices [ (PUBMED:12890666) ]. carA is Involved in the biosynthesis of carbapenam-3-carboxylate, a beta-lactam antibiotic of the carbapenem class. It catalyses the ATP-dependent formation of (3S,5S)-carbapenam-3-carboxylate from (2S,5S)-5-carboxymethylproline [ (PUBMED:12820893) (PUBMED:17658887) (PUBMED:19371088) ].

PFAM accession number:

PF09147

Interpro abstract (IPR015230):

This domain is found in the N-terminal of carbapenam-3-carboxylate synthase (carA), and is composed of two antiparallel six-stranded beta-sheets that form a sandwich, flanked on each side by two alpha-helices [ (PUBMED:12890666) ].

carA is Involved in the biosynthesis of carbapenam-3-carboxylate, a beta-lactam antibiotic of the carbapenem class. It catalyses the ATP-dependent formation of (3S,5S)-carbapenam-3-carboxylate from (2S,5S)-5-carboxymethylproline [ (PUBMED:12820893) (PUBMED:17658887) (PUBMED:19371088) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF1933