The domain within your query sequence starts at position 63 and ends at position 190; the E-value for the DUF4472 domain shown below is 5.5e-23.



PFAM accession number:PF14739
Interpro abstract (IPR029329):

This domain is found in proteins from Metazoa. Some proteins also carry kinesin-motor domains at their N terminus (IPR001752).

Proteins containing this domain include the coiled-coil domain-containing protein 78 (CCDC78), which is a component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles [(PUBMED:24075808)]. CCDC78 does not have the kinesin-motor domain. Mutations in CCDC78 genes cause Myopathy, centronuclear, 4 (CNM4), which is a congenital muscle disorder characterised by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. It may also affect distal muscles [(PUBMED:22818856)].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF4472