The domain within your query sequence starts at position 38 and ends at position 328; the E-value for the DUF4481 domain shown below is 4.4e-127.

LHNGQVLTVLRIDNTCAPISFDLGAAEEQLQAWGIQVPAEQYRNLAESALLEPQVRRYII
YNSRPMRLAFAVVFYVLVWANIYSTSQMFALGNQWAGVLLATLAAFSLTLTLVLVFERQQ
RKANTNTDLRLVAANGALLRHRVLLGVTDTVEGCQSVIQLWFVYFDLENCVQFLSDHVQE
MKRSQESLLRSRLSQLCVVMETGVSPVVEGPEDLEDAPLLPSTPGPQERPLTQTELYQLV
PEAEPEEMARQLLAVFGGYYTRLLVTSRLPQSMGTRHMDSARIPCPCQLIE

DUF4481

 DUF4481
PFAM accession number:PF14800
Interpro abstract (IPR028054):

This family of unknown function is found in eukaryotes. The human representative is transmembrane protein C9orf91. In mouse it is also known as Tmem268.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF4481