The domain within your query sequence starts at position 14 and ends at position 221; the E-value for the DUF4533 domain shown below is 2.4e-65.

RRQEVNRLHQQLLDCLSDSFQVTNKLTGVLNTHLGCRLAFIEMKSDGTIKENCDIIIQAM
TKIQKELQKIDEALKDQLEPTLYRKLQDIKERETEKIAIVQKVISVILGEATSAASAVAV
KLVGSSVTTGIISKLVSVLAHIGTSLLGSIGVAVLSLGIDMIIQAILGAVERTQLQAAIK
SYEKHLEEFKAASAKYHHAITEVATAVK

DUF4533

 DUF4533
PFAM accession number:PF15047
Interpro abstract (IPR027895):

This family of proteins is functionally uncharacterised. This family of proteins is found in mammals and includes two human proteins: C12orf60 and C12orf69.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF4533