SMART: Pfam domain DsbC

DsbC_N

PFAM accession number:	PF10411
Interpro abstract (IPR018950):	This is the N-terminal domain of the disulphide bond isomerase DsbC and DsbG. The whole molecule is V-shaped, where each arm is a DsbC monomer of two domains linked by a hinge; and the N-termini of each monomer join to form the dimer interface at the base of the V, so are vital for dimerisation [ (PUBMED:10700276) ]. DsbC is required for disulphide bond formation and functions as a disulphide bond isomerase during oxidative protein-folding in bacterial periplasm. It also has chaperone activity [ (PUBMED:16087673) ].

PFAM accession number:

PF10411

Interpro abstract (IPR018950):

This is the N-terminal domain of the disulphide bond isomerase DsbC and DsbG.

The whole molecule is V-shaped, where each arm is a DsbC monomer of two domains linked by a hinge; and the N-termini of each monomer join to form the dimer interface at the base of the V, so are vital for dimerisation [ (PUBMED:10700276) ]. DsbC is required for disulphide bond formation and functions as a disulphide bond isomerase during oxidative protein-folding in bacterial periplasm. It also has chaperone activity [ (PUBMED:16087673) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DsbC_N