The domain within your query sequence starts at position 3919 and ends at position 4642; the E-value for the Dynein_heavy domain shown below is 4.3e-163.

TPKIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPT
TPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTP
VLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVH
LAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRT
FSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVD
TWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDS
EFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDAQTPSWLGLPNNAERVLLTTQGVDMI
SKMLKMQMLEDEDDLAYAETEKKARTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSPLKR
TVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGIL
PRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISQAAASGGAKELKNIHVCLGGLFVPEAY
ITATRQYVAQANSWSLEELCLEVNVTASQSATLDACSFGVTGLKLQGATCSNNKLSLSNA
ISTVLPLTQLRWVKQTSAEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGV
AVLC

Dynein_heavy

 Dynein_heavy
PFAM accession number:PF03028
Interpro abstract (IPR004273):

This entry represents the C-terminal region of dynein heavy chain. The chain also contains ATPase activity and microtubule binding ability and acts as a motor for the movement of organelles and vesicles along microtubules. Dynein is also involved in cilia and flagella movement. The dynein subunit consists of at least two heavy chains and a number of intermediate and light chains [ (PUBMED:7866389) ]. The 380kDa motor unit of dynein belongs to the AAA class of chaperone-like ATPases. The core of the 380kDa motor unit contains a concatenated chain of six AAA modules, of which four correspond to the ATP binding sites with P-loop signatures described previously, and two are modules in which the P loop has been lost in evolution. This C-terminal domain carries the D6 region of the dynein motor where the P-loop has been lost in evolution but the general structure of a potential ATP binding site appears to be retained [ (PUBMED:11250194) ].

GO process:microtubule-based movement (GO:0007018)
GO component:dynein complex (GO:0030286)
GO function:ATP-dependent microtubule motor activity, minus-end-directed (GO:0008569)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Dynein_heavy