The domain within your query sequence starts at position 179 and ends at position 230; the E-value for the E3_UbLigase_EDD domain shown below is 9.7e-35.
VIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDED
E3_UbLigase_EDD |
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PFAM accession number: | PF11547 |
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Interpro abstract (IPR024725): | EDD (also known as UBR5), the ER ubiquitin ligase from the HECT ligases, contains an N-terminal ubiquitin-associated (UBA) domain which binds ubiquitin. Ubiquitin is recognised by helices alpha-1 and -3 in in the UBA domain. EDD is involved in DNA damage repair pathways and binds to mono-ubiquitinated proteins [ (PUBMED:17897937) ]. |
GO function: | ubiquitin binding (GO:0043130) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry E3_UbLigase_EDD