SMART: Pfam domain ENT

ENT

PFAM accession number:	PF03735
Interpro abstract (IPR005491):	The EMSY N-terminal (ENT) domain is a ~90-residue module, which is unique in the human proteome, although multiple copies are found in Arabidopsis proteins. In the plant proteins, the ENT domains are accompanied by Agenet domains, plant specific homologues of Tudor domains [ (PUBMED:14651845) (PUBMED:12575993) ]. The ENT domain consists of a unique arrangement of five alpha-helices that fold into a helical bundle arrangement. Overall, the three-dimensional structure adopts a club-like shape that consists of an extended N-terminal alpha-helix that connects to a helical bundle substructure. The ENT domain forms a homodimer via the anti-parallel packing of the long N-terminal alpha-helix from each subunit [ (PUBMED:15978617) (PUBMED:15947784) ].

PFAM accession number:

PF03735

Interpro abstract (IPR005491):

The EMSY N-terminal (ENT) domain is a ~90-residue module, which is unique in the human proteome, although multiple copies are found in Arabidopsis proteins. In the plant proteins, the ENT domains are accompanied by Agenet domains, plant specific homologues of Tudor domains [ (PUBMED:14651845) (PUBMED:12575993) ].

The ENT domain consists of a unique arrangement of five alpha-helices that fold into a helical bundle arrangement. Overall, the three-dimensional structure adopts a club-like shape that consists of an extended N-terminal alpha-helix that connects to a helical bundle substructure. The ENT domain forms a homodimer via the anti-parallel packing of the long N-terminal alpha-helix from each subunit [ (PUBMED:15978617) (PUBMED:15947784) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry ENT