The domain within your query sequence starts at position 503 and ends at position 1249; the E-value for the Enamelin domain shown below is 1.9e-303.

AANKPFVRNNVGANKPFVGTNPSSNQPFLRSNQASNKPFMRSNQASNKPFVGTNVASVGP
KQVTVSHNMKTQNPKEKSLGQKERTVTPTKDASNPWRSAKQYGINNPNYNLPRSEGSMVG
PNFNSFDQQENSYFSKGASKRVPSPNIQIQSQNLPKGIALEPRRTPFQSETKKPELKHGT
HQPAYPKKIPSPTRKHFPAERNTWNRQKILPPLKEDYGRQDENLRHPSYGSRGNIFYHEY
TNPYHNEKSQYIKSNPWDKSSPSTMMRPENPQYTMTSLDQKETEQYNEEDPIDPNEDESF
PGQSRWGDEEMNFKGNPTVRQYEGEHYASTLAKEYLPYSLSNPPKPSEDFPYSEFYPWNP
QETFPIYNPGPTIAPPVDPRSYYVNNAIGQEESTLFPSWTSWDHRNQAERQKESEPYFNR
NVWDQSINLHKSNIPNHPYSTTSPARFPKDPTWFEGENLNYDLQITSLSPPEREQLAFPD
FLPQSYPTGQNEAHLFHQSQRGSCCIGGSTGHKDNVLALQDYTSSYGLPPRKNQETSPVH
TESSYIKYARPNVSPASILPSQRNISENKLTAESPNPSPFGDGVPTVRKNTPYSGKNQLE
TGIVAFSEASSSQPKNTPCLKSDLGGDRRDVLKQFFEGSQLSERTAGLTPEQLVIGIPDK
GSGPDSIQSEVQGKEGEMQQQRPPTIMKLPCFGSNSKFHSSTTGPPINNRRPTLLNGALS
TPTESPNTLVGLATREQLKSINVDKLN

Enamelin

Enamelin
PFAM accession number:PF15362
Interpro abstract (IPR015673):

Enamelin is a secreted structural protein that acts to create dental enamel matrix. Enamelin protein is proteolytically cleaved into several products, which are identified by their molecular weights and appear to have different functions in different enamel compartments. It is not currently known how enamelin interacts with other proteins of the enamel matrix [(PUBMED:14656895)].

Enamelin mutations have been found to cause certain forms of amelogenesis imperfecta, a condition in which enamel is malformed [(PUBMED:11037750)].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Enamelin